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PKC signal amplification suppresses non-small cell lung cancer growth by promoting p21 expression and phosphorylation

Protein kinase C (PKC) activation was previously associated with oncogenic features. However, small molecule inhibitors targeting PKC have so far proved ineffective in a number of clinical trials for cancer treatment. Recent progresses have revealed that most PKC mutations detected in diverse cancer...

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Detalles Bibliográficos
Autores principales:	Liu, Shuyan, Zhang, Yayun, Yang, Qianyi, Zhang, Yingqiu, Liu, Han, Huang, Mu-Hua, Wang, Ruoyu, Lu, Faqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494247/ https://www.ncbi.nlm.nih.gov/pubmed/36158087 http://dx.doi.org/10.1016/j.heliyon.2022.e10657

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