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Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice

BACKGROUND & AIMS: Non-absorbable inhibitors of the apical sodium-dependent bile acid transporter (ASBT; also called ileal bile acid transporter [IBAT]) are recently approved or in clinical development for multiple cholestatic liver disorders and lead to a reduction in pruritus and (markers for)...

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Detalles Bibliográficos
Autores principales:	Kunst, Roni F., de Waart, Dirk R., Wolters, Frank, Duijst, Suzanne, Vogels, Esther W., Bolt, Isabelle, Verheij, Joanne, Beuers, Ulrich, Oude Elferink, Ronald P.J., van de Graaf, Stan F.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494276/ https://www.ncbi.nlm.nih.gov/pubmed/36160754 http://dx.doi.org/10.1016/j.jhepr.2022.100573

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