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P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units

POSTER SESSION 2, SEPTEMBER 22, 2022, 12:30 PM - 1:30 PM:   BACKGROUNDS: The pandemic of COVID-19 has created a global public health crisis. ICU patients with COVID-19 are prone to infections of bacterial and/or fungal origins due to several risk factors. Consequently, the current study was conducte...

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Autores principales: Sarvestani, Hasti Kamali, Khansari, Mahmoud, Rafat, Zahra, Abdollahi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494482/
http://dx.doi.org/10.1093/mmy/myac072.P211
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author Sarvestani, Hasti Kamali
Khansari, Mahmoud
Rafat, Zahra
Abdollahi, Alireza
author_facet Sarvestani, Hasti Kamali
Khansari, Mahmoud
Rafat, Zahra
Abdollahi, Alireza
author_sort Sarvestani, Hasti Kamali
collection PubMed
description POSTER SESSION 2, SEPTEMBER 22, 2022, 12:30 PM - 1:30 PM:   BACKGROUNDS: The pandemic of COVID-19 has created a global public health crisis. ICU patients with COVID-19 are prone to infections of bacterial and/or fungal origins due to several risk factors. Consequently, the current study was conducted to evaluate the frequency, demographic characteristics, underlying conditions, and etiologic agents of fungal and bacterial co-infections of the respiratory tract among ICU patients with COVID-19 in Iran. MATERIALS AND METHODS: From May to October 2020, sputa and endotracheal aspirates were collected from ICU patients hospitalized with COVID-19 who also were suspected of bacterial and/or fungal co-infections according to inclusion criteria. The etiologic agents of bacterial co-infections were identified using the VITEK 2 identification method. For fungal identification, all samples were analyzed by direct microscopy using KOH 10% and culture. Furthermore, all isolates were subjected to the sequencing method. RESULTS: A total of 73 lung specimens were obtained from patients who met the inclusion criteria. Of these, in 15 cases (20.54%) fungal and/or bacterial co-infections were confirmed. Males were more infected (73.33%) and all of them were between 49 and 79 years. Candida albicans (n = 8, 61.53%) and Klebsiella pneumonia (n = 5, 38.46%) were the most frequent etiologic agents related to fungal and bacterial co-infections, respectively. Pneumonia (n = 15, 100%) and diabetes mellitus (n = 8, 53.33%) were documented as the most prevalent underlying conditions. In the current study, 3 out of 15 patients (20%) died. CONCLUSION: The frequency of bacterial co-infections of the respiratory tract in ICU patients hospitalized with COVID-19 was relatively high. According to the results, one of the causes of death in these patients could be a secondary infection.
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spelling pubmed-94944822022-09-26 P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units Sarvestani, Hasti Kamali Khansari, Mahmoud Rafat, Zahra Abdollahi, Alireza Med Mycol Oral Presentations POSTER SESSION 2, SEPTEMBER 22, 2022, 12:30 PM - 1:30 PM:   BACKGROUNDS: The pandemic of COVID-19 has created a global public health crisis. ICU patients with COVID-19 are prone to infections of bacterial and/or fungal origins due to several risk factors. Consequently, the current study was conducted to evaluate the frequency, demographic characteristics, underlying conditions, and etiologic agents of fungal and bacterial co-infections of the respiratory tract among ICU patients with COVID-19 in Iran. MATERIALS AND METHODS: From May to October 2020, sputa and endotracheal aspirates were collected from ICU patients hospitalized with COVID-19 who also were suspected of bacterial and/or fungal co-infections according to inclusion criteria. The etiologic agents of bacterial co-infections were identified using the VITEK 2 identification method. For fungal identification, all samples were analyzed by direct microscopy using KOH 10% and culture. Furthermore, all isolates were subjected to the sequencing method. RESULTS: A total of 73 lung specimens were obtained from patients who met the inclusion criteria. Of these, in 15 cases (20.54%) fungal and/or bacterial co-infections were confirmed. Males were more infected (73.33%) and all of them were between 49 and 79 years. Candida albicans (n = 8, 61.53%) and Klebsiella pneumonia (n = 5, 38.46%) were the most frequent etiologic agents related to fungal and bacterial co-infections, respectively. Pneumonia (n = 15, 100%) and diabetes mellitus (n = 8, 53.33%) were documented as the most prevalent underlying conditions. In the current study, 3 out of 15 patients (20%) died. CONCLUSION: The frequency of bacterial co-infections of the respiratory tract in ICU patients hospitalized with COVID-19 was relatively high. According to the results, one of the causes of death in these patients could be a secondary infection. Oxford University Press 2022-09-20 /pmc/articles/PMC9494482/ http://dx.doi.org/10.1093/mmy/myac072.P211 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Oral Presentations
Sarvestani, Hasti Kamali
Khansari, Mahmoud
Rafat, Zahra
Abdollahi, Alireza
P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units
title P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units
title_full P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units
title_fullStr P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units
title_full_unstemmed P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units
title_short P211 Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units
title_sort p211 fungal and bacterial co-infections of the respiratory tract among patients with covid-19 hospitalized in intensive care units
topic Oral Presentations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494482/
http://dx.doi.org/10.1093/mmy/myac072.P211
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