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Recombinant COVID-19 vaccine based on recombinant RBD/Nucleoprotein and saponin adjuvant induces long-lasting neutralizing antibodies and cellular immunity

SARS-CoV-2 has caused a global pandemic, infecting millions of people. An effective preventive vaccine against this virus is urgently needed. Here, we designed and developed a novel formulated recombinant receptor-binding domain (RBD) nucleocapsid (N) recombinant vaccine candidates. The RBD and N we...

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Detalles Bibliográficos
Autores principales: Ghaemi, Amir, Roshani Asl, Parisa, Zargaran, Hedieh, Ahmadi, Delaram, Hashimi, Asim Ali, Abdolalipour, Elahe, Bathaeian, Sahar, Miri, Seyed Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494508/
https://www.ncbi.nlm.nih.gov/pubmed/36159845
http://dx.doi.org/10.3389/fimmu.2022.974364

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