Discovery of JAK2/3 Inhibitors from Quinoxalinone-Containing Compounds

[Image: see text] Janus kinases (JAKs) are involved in a wide variety of cell signaling associated with T-cell and B-cell mediated diseases. The pathogenesis of common lymphoid-derived diseases and leukemia cancer has been implicated in JAK2 and JAK3. Therefore, to decrease the risk of these disease...

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Detalles Bibliográficos
Autores principales: Sanachai, Kamonpan, Mahalapbutr, Panupong, Tabtimmai, Lueacha, Seetaha, Supaphorn, Kittikool, Tanakorn, Yotphan, Sirilata, Choowongkomon, Kiattawee, Rungrotmongkol, Thanyada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494680/
https://www.ncbi.nlm.nih.gov/pubmed/36157733
http://dx.doi.org/10.1021/acsomega.2c04769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494680/
https://www.ncbi.nlm.nih.gov/pubmed/36157733
http://dx.doi.org/10.1021/acsomega.2c04769

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