Chemoinformatic Design and Profiling of Derivatives of Dasabuvir, Efavirenz, and Tipranavir as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase and Methyltransferase

[Image: see text] Zika virus (ZIKV) infection is one of the mosquito-borne flaviviruses of human importance with more than 2 million suspected cases and more than 1 million people infected in about 30 countries. There are reported inhibitors of the zika virus replication machinery, but no approved e...

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Autores principales: Ezeh, Madeleine I., Okonkwo, Onyinyechi E., Okpoli, Innocent N., Orji, Chima E., Modozie, Benjamin U., Onyema, Augustine C., Ezebuo, Fortunatus C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494688/
https://www.ncbi.nlm.nih.gov/pubmed/36157724
http://dx.doi.org/10.1021/acsomega.2c03945

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