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Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery

Biohybrid micro- and nanorobots are integrated tiny machines from biological components and artificial components. They can possess the advantages of onboard actuation, sensing, control, and implementation of multiple medical tasks such as targeted drug delivery, single-cell manipulation, and cell m...

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Detalles Bibliográficos
Autores principales: Li, Jinhua, Dekanovsky, Lukas, Khezri, Bahareh, Wu, Bing, Zhou, Huaijuan, Sofer, Zdenek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494704/
https://www.ncbi.nlm.nih.gov/pubmed/36285309
http://dx.doi.org/10.34133/2022/9824057
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author Li, Jinhua
Dekanovsky, Lukas
Khezri, Bahareh
Wu, Bing
Zhou, Huaijuan
Sofer, Zdenek
author_facet Li, Jinhua
Dekanovsky, Lukas
Khezri, Bahareh
Wu, Bing
Zhou, Huaijuan
Sofer, Zdenek
author_sort Li, Jinhua
collection PubMed
description Biohybrid micro- and nanorobots are integrated tiny machines from biological components and artificial components. They can possess the advantages of onboard actuation, sensing, control, and implementation of multiple medical tasks such as targeted drug delivery, single-cell manipulation, and cell microsurgery. This review paper is to give an overview of biohybrid micro- and nanorobots for smart drug delivery applications. First, a wide range of biohybrid micro- and nanorobots comprising different biological components are reviewed in detail. Subsequently, the applications of biohybrid micro- and nanorobots for active drug delivery are introduced to demonstrate how such biohybrid micro- and nanorobots are being exploited in the field of medicine and healthcare. Lastly, key challenges to be overcome are discussed to pave the way for the clinical translation and application of the biohybrid micro- and nanorobots.
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spelling pubmed-94947042022-10-24 Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery Li, Jinhua Dekanovsky, Lukas Khezri, Bahareh Wu, Bing Zhou, Huaijuan Sofer, Zdenek Cyborg Bionic Syst Review Article Biohybrid micro- and nanorobots are integrated tiny machines from biological components and artificial components. They can possess the advantages of onboard actuation, sensing, control, and implementation of multiple medical tasks such as targeted drug delivery, single-cell manipulation, and cell microsurgery. This review paper is to give an overview of biohybrid micro- and nanorobots for smart drug delivery applications. First, a wide range of biohybrid micro- and nanorobots comprising different biological components are reviewed in detail. Subsequently, the applications of biohybrid micro- and nanorobots for active drug delivery are introduced to demonstrate how such biohybrid micro- and nanorobots are being exploited in the field of medicine and healthcare. Lastly, key challenges to be overcome are discussed to pave the way for the clinical translation and application of the biohybrid micro- and nanorobots. AAAS 2022-02-10 /pmc/articles/PMC9494704/ /pubmed/36285309 http://dx.doi.org/10.34133/2022/9824057 Text en Copyright © 2022 Jinhua Li et al. https://creativecommons.org/licenses/by/4.0/Exclusive Licensee Beijing Institute of Technology Press. Distributed under a Creative Commons Attribution License (CC BY 4.0).
spellingShingle Review Article
Li, Jinhua
Dekanovsky, Lukas
Khezri, Bahareh
Wu, Bing
Zhou, Huaijuan
Sofer, Zdenek
Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery
title Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery
title_full Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery
title_fullStr Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery
title_full_unstemmed Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery
title_short Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery
title_sort biohybrid micro- and nanorobots for intelligent drug delivery
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494704/
https://www.ncbi.nlm.nih.gov/pubmed/36285309
http://dx.doi.org/10.34133/2022/9824057
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