An integrated microfluidics platform with high-throughput single-cell cloning array and concentration gradient generator for efficient cancer drug effect screening

BACKGROUND: Tumor cell heterogeneity mediated drug resistance has been recognized as the stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single-cell level in a high-throughput way is thus of great value for developing precision therapy. However, current techn...

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Detalles Bibliográficos
Autores principales: Wang, Biao, He, Bang-Shun, Ruan, Xiao-Lan, Zhu, Jiang, Hu, Rui, Wang, Jie, Li, Ying, Yang, Yun-Huang, Liu, Mai-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494811/
https://www.ncbi.nlm.nih.gov/pubmed/36131323
http://dx.doi.org/10.1186/s40779-022-00409-9

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