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Progress in Genomic Mating in Domestic Animals

SIMPLE SUMMARY: Since animal domestication, breeders have been selecting candidates for breeding based on phenotypic performance. Estimating breeding values through the best linear unbiased prediction method represents a revolutionary shift in animal breeding. On this basis, selection and mating are...

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Autores principales: Zhang, Pengfei, Qiu, Xiaotian, Wang, Lixian, Zhao, Fuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494983/
https://www.ncbi.nlm.nih.gov/pubmed/36139166
http://dx.doi.org/10.3390/ani12182306
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author Zhang, Pengfei
Qiu, Xiaotian
Wang, Lixian
Zhao, Fuping
author_facet Zhang, Pengfei
Qiu, Xiaotian
Wang, Lixian
Zhao, Fuping
author_sort Zhang, Pengfei
collection PubMed
description SIMPLE SUMMARY: Since animal domestication, breeders have been selecting candidates for breeding based on phenotypic performance. Estimating breeding values through the best linear unbiased prediction method represents a revolutionary shift in animal breeding. On this basis, selection and mating are utilized to improve the production level of animals. The application of genomic selection has once again revolutionized animal breeding methods. However, although this kind of truncated selection based on breeding values can significantly improve genetic gain, the genetic relationship between individuals with a high breeding value is usually closed, and the probability of being co-selected is greater, which will lead to a rapid increase in the rate of inbreeding in the population. Reduced genetic variation is not conducive to long-term sustainable breeding, so a trade-off between genetic gain and inbreeding is required. Genomic mating is the use of candidate individuals’ genomic information to implement optimized breeding and mating, which can effectively control the rate of inbreeding in the population and achieve long-term and sustainable genetic gain. It is more suitable for modern animal breeding, especially for conservation and genetic improvement of local domestic animal breeds. ABSTRACT: Selection is a continuous process that can influence the distribution of target traits in a population. From the perspective of breeding, elite individuals are selected for breeding, which is called truncated selection. With the introduction and application of the best linear unbiased prediction (BLUP) method, breeders began to use pedigree-based estimated breeding values (EBV) to select candidates for the genetic improvement of complex traits. Although truncated selection based on EBV can significantly improve the genetic progress, the genetic relationships between individuals with a high breeding value are usually closed, and the probability of being co-selected is greater, which will lead to a rapid increase in the level of inbreeding in the population. Reduced genetic variation is not conducive to long-term sustainable breeding, so a trade-off between genetic progress and inbreeding is required. As livestock and poultry breeding enters the genomic era, using genomic information to obtain optimal mating plans has formally been proposed by Akdemir et al., a method called genomic mating (GM). GM is more accurate and reliable than using pedigree information. Moreover, it can effectively control the inbreeding level of the population and achieve long-term and sustainable genetic gain. Hence, GM is more suitable for modern animal breeding, especially for local livestock and poultry breed conservation and genetic improvement. This review mainly summarized the principle of genomic mating, the methodology and usage of genomic mating, and the progress of its application in livestock and poultry.
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spelling pubmed-94949832022-09-23 Progress in Genomic Mating in Domestic Animals Zhang, Pengfei Qiu, Xiaotian Wang, Lixian Zhao, Fuping Animals (Basel) Review SIMPLE SUMMARY: Since animal domestication, breeders have been selecting candidates for breeding based on phenotypic performance. Estimating breeding values through the best linear unbiased prediction method represents a revolutionary shift in animal breeding. On this basis, selection and mating are utilized to improve the production level of animals. The application of genomic selection has once again revolutionized animal breeding methods. However, although this kind of truncated selection based on breeding values can significantly improve genetic gain, the genetic relationship between individuals with a high breeding value is usually closed, and the probability of being co-selected is greater, which will lead to a rapid increase in the rate of inbreeding in the population. Reduced genetic variation is not conducive to long-term sustainable breeding, so a trade-off between genetic gain and inbreeding is required. Genomic mating is the use of candidate individuals’ genomic information to implement optimized breeding and mating, which can effectively control the rate of inbreeding in the population and achieve long-term and sustainable genetic gain. It is more suitable for modern animal breeding, especially for conservation and genetic improvement of local domestic animal breeds. ABSTRACT: Selection is a continuous process that can influence the distribution of target traits in a population. From the perspective of breeding, elite individuals are selected for breeding, which is called truncated selection. With the introduction and application of the best linear unbiased prediction (BLUP) method, breeders began to use pedigree-based estimated breeding values (EBV) to select candidates for the genetic improvement of complex traits. Although truncated selection based on EBV can significantly improve the genetic progress, the genetic relationships between individuals with a high breeding value are usually closed, and the probability of being co-selected is greater, which will lead to a rapid increase in the level of inbreeding in the population. Reduced genetic variation is not conducive to long-term sustainable breeding, so a trade-off between genetic progress and inbreeding is required. As livestock and poultry breeding enters the genomic era, using genomic information to obtain optimal mating plans has formally been proposed by Akdemir et al., a method called genomic mating (GM). GM is more accurate and reliable than using pedigree information. Moreover, it can effectively control the inbreeding level of the population and achieve long-term and sustainable genetic gain. Hence, GM is more suitable for modern animal breeding, especially for local livestock and poultry breed conservation and genetic improvement. This review mainly summarized the principle of genomic mating, the methodology and usage of genomic mating, and the progress of its application in livestock and poultry. MDPI 2022-09-06 /pmc/articles/PMC9494983/ /pubmed/36139166 http://dx.doi.org/10.3390/ani12182306 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Pengfei
Qiu, Xiaotian
Wang, Lixian
Zhao, Fuping
Progress in Genomic Mating in Domestic Animals
title Progress in Genomic Mating in Domestic Animals
title_full Progress in Genomic Mating in Domestic Animals
title_fullStr Progress in Genomic Mating in Domestic Animals
title_full_unstemmed Progress in Genomic Mating in Domestic Animals
title_short Progress in Genomic Mating in Domestic Animals
title_sort progress in genomic mating in domestic animals
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9494983/
https://www.ncbi.nlm.nih.gov/pubmed/36139166
http://dx.doi.org/10.3390/ani12182306
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