Integrated genomic, transcriptomic and metabolomic analysis reveals MDH2 mutation-induced metabolic disorder in recurrent focal segmental glomerulosclerosis

Focal segmental glomerulosclerosis (FSGS) has an over 30% risk of recurrence after kidney transplantation (Ktx) and is associated with an extremely high risk of graft loss. However, mechanisms remain largely unclear. Thus, this study identifies novel genes related to the recurrence of FSGS (rFSGS)....

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Detalles Bibliográficos
Autores principales: Shen, Qixia, Teng, Lisha, Wang, Yucheng, Guo, Luying, Xu, Feng, Huang, Hongfeng, Xie, Wenqing, Zhou, Qin, Chen, Ying, Wang, Junwen, Mao, Youying, Chen, Jianghua, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495259/
https://www.ncbi.nlm.nih.gov/pubmed/36159820
http://dx.doi.org/10.3389/fimmu.2022.962986

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