Tenovin-1 Ameliorates Renal Fibrosis in High-Fat-Diet-Induced Diabetic Nephropathy via Antioxidant and Anti-Inflammatory Pathways

High-fat diet (HFD)-induced obesity has been involved in the development of diabetic nephropathy (DN). Tenovin-1, a potent selective SIRT1/2 inhibitor, regulates various target proteins. The present study evaluated the protective effect of Tenovin-1 against renal fibrosis in HFD-induced Zucker diabe...

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Detalles Bibliográficos
Autores principales: Kundu, Amit, Gali, Sreevarsha, Sharma, Swati, Park, Jae Hyeon, Kyung, So Young, Kacew, Sam, Kim, In Su, Lee, Kwang Youl, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495519/
https://www.ncbi.nlm.nih.gov/pubmed/36139886
http://dx.doi.org/10.3390/antiox11091812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495519/
https://www.ncbi.nlm.nih.gov/pubmed/36139886
http://dx.doi.org/10.3390/antiox11091812

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