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Olanzapine Ameliorates Ischemic Stroke-like Pathology in Gerbils and H(2)O(2)-Induced Neurotoxicity in SH-SY5Y Cells via Inhibiting the MAPK Signaling Pathway

Olanzapine (OLNZ) is used to treat psychotic disorders. To look into the neurological basis of this phenomenon, we investigated the neuroprotective effects of OLNZ in gerbils and SH-SY5Y cells. Gerbils were subjected to transient global cerebral ischemia (TGCI) by blocking both common carotid arteri...

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Detalles Bibliográficos
Autores principales: Islam, Md Sadikul, Shin, Ha-Young, Yoo, Yeo-Jin, Kim, Ryunhee, Jang, Young-Jin, Akanda, Md Rashedunnabi, Tae, Hyun-Jin, Kim, In-Shik, Ahn, Dongchoon, Park, Byung-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495525/
https://www.ncbi.nlm.nih.gov/pubmed/36139770
http://dx.doi.org/10.3390/antiox11091697