Adipocyte-Specific Laminin Alpha 4 Deletion Preserves Adipose Tissue Health despite Increasing Adiposity

Laminins are heterotrimeric glycoproteins with structural and functional roles in basement membranes. The predominant laminin alpha chain found in adipocyte basement membranes is laminin α4 (LAMA4). Global LAMA4 deletion in mice leads to reduced adiposity and increased energy expenditure, but also r...

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Detalles Bibliográficos
Autores principales: Bailey, Jennifer L., Burk, David H., Burke, Susan J., Reed, Scott D., Ghosh, Sujoy, Elks, Carrie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495590/
https://www.ncbi.nlm.nih.gov/pubmed/36140178
http://dx.doi.org/10.3390/biomedicines10092077

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