Cargando…

Metabolic Profile Variations along the Differentiation of Human-Induced Pluripotent Stem Cells to Dopaminergic Neurons

In recent years, the availability of induced pluripotent stem cell-based neuronal models has opened new perspectives on the study and therapy of neurological diseases such as Parkinson’s disease. In particular, P. Zhang set up a protocol to efficiently generate dopaminergic neurons from induced plur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carsana, Emma Veronica, Audano, Matteo, Breviario, Silvia, Pedretti, Silvia, Aureli, Massimo, Lunghi, Giulia, Mitro, Nico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495704/ https://www.ncbi.nlm.nih.gov/pubmed/36140170 http://dx.doi.org/10.3390/biomedicines10092069

Ejemplares similares

“The Loss of Golden Touch”: Mitochondria-Organelle Interactions, Metabolism, and Cancer
por: Audano, Matteo, et al.
Publicado: (2020)

Rewiring of Glucose and Lipid Metabolism Induced by G Protein-Coupled Receptor 17 Silencing Enables the Transition of Oligodendrocyte Progenitors to Myelinating Cells
por: Marangon, Davide, et al.
Publicado: (2022)

Sustained IP3-linked Ca(2+) signaling promotes progression of triple negative breast cancer cells by regulating fatty acid metabolism
por: Filadi, Riccardo, et al.
Publicado: (2023)

Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction
por: Audano, Matteo, et al.
Publicado: (2021)

Metabolic control of DNA methylation in naïve pluripotent cells
por: Betto, Riccardo M, et al.
Publicado: (2021)

Regulatory mechanisms of the early phase of white adipocyte differentiation: an overview
por: Audano, M., et al.
Publicado: (2022)

Butyrate prevents visceral adipose tissue inflammation and metabolic alterations in a Friedreich’s ataxia mouse model
por: Turchi, Riccardo, et al.
Publicado: (2023)

Intermittent Fasting Applied in Combination with Rotenone Treatment Exacerbates Dopamine Neurons Degeneration in Mice
por: Tatulli, Giuseppe, et al.
Publicado: (2018)

Origin of the Induced Pluripotent Stem Cells Affects Their Differentiation into Dopaminergic Neurons
por: Chlebanowska, Paula, et al.
Publicado: (2020)

Pluripotent Stem Cell-derived Dopaminergic Neurons for Studying Developmental Neurotoxicity
por: Kreutz, Anna, et al.
Publicado: (2023)

Histone Deacetylase 3 Regulates Adipocyte Phenotype at Early Stages of Differentiation
por: Cricrí, Dalma, et al.
Publicado: (2021)

PPAR Agonists and Metabolic Syndrome: An Established Role?
por: Botta, Margherita, et al.
Publicado: (2018)

Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation
por: Okarmus, Justyna, et al.
Publicado: (2020)

Differentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells
por: Grow, Douglas A., et al.
Publicado: (2016)

Pluripotent stem cell derived dopaminergic subpopulations model the selective neuron degeneration in Parkinson’s disease
por: Oosterveen, Tony, et al.
Publicado: (2021)

Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function
por: Audano, Matteo, et al.
Publicado: (2014)

GM1 Oligosaccharide Efficacy in Parkinson’s Disease: Protection against MPTP
por: Fazzari, Maria, et al.
Publicado: (2023)

Liver‐directed gene therapy for ornithine aminotransferase deficiency
por: Boffa, Iolanda, et al.
Publicado: (2023)

Sphingolipids and plasma membrane hydrolases in human primary bronchial cells during differentiation and their altered patterns in cystic fibrosis
por: Loberto, Nicoletta, et al.
Publicado: (2020)

Elovl5 is required for proper action potential conduction along peripheral myelinated fibers
por: Hoxha, Eriola, et al.
Publicado: (2021)

Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A
por: Carsana, Emma Veronica, et al.
Publicado: (2022)

A Comprehensive Analysis of Protocols for Deriving Dopaminergic Neurons from Human Pluripotent Stem Cells
por: Marton, Rebecca M., et al.
Publicado: (2018)

Protocol for measurement of calcium dysregulation in human induced pluripotent stem cell-derived dopaminergic neurons
por: Yin, Xiling, et al.
Publicado: (2021)

Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons
por: Sheta, Razan, et al.
Publicado: (2023)

Oxidative Pentose Phosphate Pathway Controls Vascular Mural Cell Coverage by Regulating Extracellular Matrix Composition
por: Facchinello, Nicola, et al.
Publicado: (2022)

Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver
por: Della Torre, Sara, et al.
Publicado: (2018)

Hepatic ERα accounts for sex differences in the ability to cope with an excess of dietary lipids
por: Meda, Clara, et al.
Publicado: (2019)

Transcriptomic Profile Reveals Deregulation of Hearing-Loss Related Genes in Vestibular Schwannoma Cells Following Electromagnetic Field Exposure
por: Colciago, Alessandra, et al.
Publicado: (2021)

Exploring pre-degenerative alterations in humans using induced pluripotent stem cell-derived dopaminergic neurons
por: Bono, Federica, et al.
Publicado: (2017)

Automated and manual patch clamp data of human induced pluripotent stem cell-derived dopaminergic neurons
por: Franz, Denise, et al.
Publicado: (2017)

High-throughput generation of midbrain dopaminergic neuron organoids from reporter human pluripotent stem cells
por: Sarrafha, Lily, et al.
Publicado: (2021)

Modulation of Notch Signaling at Early Stages of Differentiation of Human Induced Pluripotent Stem Cells to Dopaminergic Neurons
por: Katolikova, Nataliia V., et al.
Publicado: (2023)

PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction
por: Da Dalt, Lorenzo, et al.
Publicado: (2021)

Ca(2+) overload- and ROS-associated mitochondrial dysfunction contributes to δ-tocotrienol-mediated paraptosis in melanoma cells
por: Raimondi, Michela, et al.
Publicado: (2021)

Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model
por: Di Meo, Ivano, et al.
Publicado: (2020)

β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration
por: Lunghi, Giulia, et al.
Publicado: (2022)

Mitochondrial Dysregulation and Impaired Autophagy in iPSC-Derived Dopaminergic Neurons of Multiple System Atrophy
por: Monzio Compagnoni, Giacomo, et al.
Publicado: (2018)

Efficient Generation of Functional Dopaminergic Neurons from Human Induced Pluripotent Stem Cells Under Defined Conditions
por: Swistowski, Andrzej, et al.
Publicado: (2010)

Systemic administration of valproic acid and zonisamide promotes differentiation of induced pluripotent stem cell–derived dopaminergic neurons
por: Yoshikawa, Tatsuya, et al.
Publicado: (2013)

Zonisamide promotes survival of human‐induced pluripotent stem cell‐derived dopaminergic neurons in the striatum of female rats
por: Miyawaki, Yoshifumi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_u1r778th9a4h7bc4noijak7h8b