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METTL14-dependent m(6)A modification controls iNKT cell development and function

N(6)-methyladenosine (m(6)A), the most common form of RNA modification, controls CD4(+) T cell homeostasis by targeting the IL-7/STAT5/SOCS signaling pathways. The role of m(6)A modification in unconventional T cell development remains unknown. Using mice with T cell-specific deletion of RNA methylt...

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Detalles Bibliográficos
Autores principales: Cao, Liang, Morgun, Eva, Genardi, Samantha, Visvabharathy, Lavanya, Cui, Yongyong, Huang, Haochu, Wang, Chyung-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495716/
https://www.ncbi.nlm.nih.gov/pubmed/35926466
http://dx.doi.org/10.1016/j.celrep.2022.111156

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