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Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future
As a safe and minimal-invasive modality, thermal therapy has become an effective treatment in cancer treatment. Other than killing the tumor cells or destroying the tumor entirely, the thermal modality results in profound molecular, cellular and biological effects on both the targeted tissue, surrou...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495761/ https://www.ncbi.nlm.nih.gov/pubmed/36135020 http://dx.doi.org/10.3390/bioengineering9090474 |
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author | Dai, Qizheng Cao, Bo Zhao, Shiqing Zhang, Aili |
author_facet | Dai, Qizheng Cao, Bo Zhao, Shiqing Zhang, Aili |
author_sort | Dai, Qizheng |
collection | PubMed |
description | As a safe and minimal-invasive modality, thermal therapy has become an effective treatment in cancer treatment. Other than killing the tumor cells or destroying the tumor entirely, the thermal modality results in profound molecular, cellular and biological effects on both the targeted tissue, surrounding environments, and even the whole body, which has triggered the combination of the thermal therapy with other traditional therapies as chemotherapy and radiation therapy or new therapies like immunotherapy, gene therapy, etc. The combined treatments have shown encouraging therapeutic effects both in research and clinic. In this review, we have summarized the outcomes of the existing synergistic therapies, the underlying mechanisms that lead to these improvements, and the latest research in the past five years. Limitations and future directions of synergistic thermal therapy are also discussed. |
format | Online Article Text |
id | pubmed-9495761 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94957612022-09-23 Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future Dai, Qizheng Cao, Bo Zhao, Shiqing Zhang, Aili Bioengineering (Basel) Review As a safe and minimal-invasive modality, thermal therapy has become an effective treatment in cancer treatment. Other than killing the tumor cells or destroying the tumor entirely, the thermal modality results in profound molecular, cellular and biological effects on both the targeted tissue, surrounding environments, and even the whole body, which has triggered the combination of the thermal therapy with other traditional therapies as chemotherapy and radiation therapy or new therapies like immunotherapy, gene therapy, etc. The combined treatments have shown encouraging therapeutic effects both in research and clinic. In this review, we have summarized the outcomes of the existing synergistic therapies, the underlying mechanisms that lead to these improvements, and the latest research in the past five years. Limitations and future directions of synergistic thermal therapy are also discussed. MDPI 2022-09-15 /pmc/articles/PMC9495761/ /pubmed/36135020 http://dx.doi.org/10.3390/bioengineering9090474 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Dai, Qizheng Cao, Bo Zhao, Shiqing Zhang, Aili Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future |
title | Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future |
title_full | Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future |
title_fullStr | Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future |
title_full_unstemmed | Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future |
title_short | Synergetic Thermal Therapy for Cancer: State-of-the-Art and the Future |
title_sort | synergetic thermal therapy for cancer: state-of-the-art and the future |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495761/ https://www.ncbi.nlm.nih.gov/pubmed/36135020 http://dx.doi.org/10.3390/bioengineering9090474 |
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