Genome-Scale CRISPR Knockout Screening Identifies BACH1 as a Key Regulator of Aflatoxin B(1)-Induced Oxidative Damage

Aflatoxin B(1) (AFB(1)) is amongst the mycotoxins commonly affecting human and animal health, raising global food safety and control concerns. The mechanisms underlying AFB(1) toxicity are poorly understood. Moreover, antidotes against AFB(1) are lacking. Genome-wide CRISPR/Cas9 knockout screening i...

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Detalles Bibliográficos
Autores principales: Zhang, Jinfu, Hu, Siyi, Zhao, Changzhi, Zhou, Yuan, Zhang, Lu, Liu, Hailong, Zhou, Peng, Li, Sheng, Fu, Liangliang, Zheng, Zhuqing, Xiang, Yue, Xu, Xuewen, Ruan, Jinxue, Li, Xinyun, Sun, Lvhui, Cao, Gang, Zhao, Shuhong, Wang, Xu, Xie, Shengsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495794/
https://www.ncbi.nlm.nih.gov/pubmed/36139865
http://dx.doi.org/10.3390/antiox11091787

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