γ-Glutamylcysteine Exerts Neuroprotection Effects against Cerebral Ischemia/Reperfusion Injury through Inhibiting Lipid Peroxidation and Ferroptosis

Ferroptosis is a non-apoptotic form of cell death driven by iron-dependent lipid peroxidation. Recent evidence indicates that inhibiting ferroptosis could alleviate cerebral ischemia/reperfusion (CIR) injury. γ-glutamylcysteine (γ-GC), an intermediate of glutathione (GSH) synthesis, can upregulate G...

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Detalles Bibliográficos
Autores principales: Zhang, Ruyi, Lei, Jianzhen, Chen, Luyao, Wang, Yanan, Yang, Guocui, Yin, Zhimin, Luo, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495808/
https://www.ncbi.nlm.nih.gov/pubmed/36139727
http://dx.doi.org/10.3390/antiox11091653

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