Transcriptomics and Proteomics Analyses Reveal JAK Signaling and Inflammatory Phenotypes during Cellular Senescence in Blind Mole Rats: The Reflections of Superior Biology

SIMPLE SUMMARY: Blind mole rats (BMR) (Spalax, Nannospalax sp.) are extraordinary organisms with cancer resistance and a long lifespan for their size. Cellular senescence is a condition in which cells cease dividing irreversibly and secrete proinflammatory cytokines. To understand the mechanisms beh...

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Detalles Bibliográficos
Autores principales: Inci, Nurcan, Akyildiz, Erdogan Oguzhan, Bulbul, Abdullah Alper, Turanli, Eda Tahir, Akgun, Emel, Baykal, Ahmet Tarik, Colak, Faruk, Bozaykut, Perinur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495822/
https://www.ncbi.nlm.nih.gov/pubmed/36138732
http://dx.doi.org/10.3390/biology11091253

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