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Membranolytic Mechanism of Amphiphilic Antimicrobial β-Stranded [KL](n) Peptides

Amphipathic peptides can act as antibiotics due to membrane permeabilization. KL peptides with the repetitive sequence [Lys-Leu](n)-NH(2) form amphipathic β-strands in the presence of lipid bilayers. As they are known to kill bacteria in a peculiar length-dependent manner, we suggest here several di...

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Detalles Bibliográficos
Autores principales: Schweigardt, Fabian, Strandberg, Erik, Wadhwani, Parvesh, Reichert, Johannes, Bürck, Jochen, Cravo, Haroldo L. P., Burger, Luisa, Ulrich, Anne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495826/
https://www.ncbi.nlm.nih.gov/pubmed/36140173
http://dx.doi.org/10.3390/biomedicines10092071