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Surgical Classification for Preclinical Rat Femoral Bone Defect Model: Standardization Based on Systematic Review, Anatomical Analysis and Virtual Surgery

Though surgical techniques profoundly influence in vivo experiments, significant heterogeneity exists in current surgeries for inducing rat femoral bone defects. Such variations reduce the reproducibility and comparability of preclinical studies, and are detrimental to clinical translation. The purp...

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Detalles Bibliográficos
Autores principales: Sun, Yu, Helmholz, Heike, Willumeit-Römer, Regine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9495991/
https://www.ncbi.nlm.nih.gov/pubmed/36135022
http://dx.doi.org/10.3390/bioengineering9090476

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