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Epigenetic Suppression of the IL-7 Pathway in Progressive Glioblastoma

Background: Immune evasion in glioblastoma (GBM) shields cancer cells from cytotoxic immune response. Methods: We investigated CpG methylation in promoters, genes, and pathways in 22 pairs of formalin-fixed paraffin-embedded sequential (FFPE) GBM using restricted resolution bisulfite sequencing (RRB...

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Detalles Bibliográficos
Autores principales: Tompa, Marton, Kraboth, Zoltan, Galik, Bence, Kajtar, Bela, Gyenesei, Attila, Kalman, Bernadette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496096/
https://www.ncbi.nlm.nih.gov/pubmed/36140275
http://dx.doi.org/10.3390/biomedicines10092174

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