Cargando…

Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma

Inhaled corticosteroids (ICS) remain the mainstay of asthma treatment, along with bronchodilators serving as control agents in combination with ICS or reliever therapy. Although current pharmacological treatments improve symptom control, health status, and the frequency and severity of exacerbations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Calzetta, Luigino, Aiello, Marina, Frizzelli, Annalisa, Pistocchini, Elena, Ritondo, Beatrice Ludovica, Rogliani, Paola, Chetta, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Systematic Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496184/ https://www.ncbi.nlm.nih.gov/pubmed/36140430 http://dx.doi.org/10.3390/biomedicines10092330

Ejemplares similares

Impact of Sex on Proper Use of Inhaler Devices in Asthma and COPD: A Systematic Review and Meta-Analysis
por: Calzetta, Luigino, et al.
Publicado: (2022)

The Impact of Monoclonal Antibodies on Airway Smooth Muscle Contractility in Asthma: A Systematic Review
por: Calzetta, Luigino, et al.
Publicado: (2021)

Oral Corticosteroids Dependence and Biologic Drugs in Severe Asthma: Myths or Facts? A Systematic Review of Real-World Evidence
por: Calzetta, Luigino, et al.
Publicado: (2021)

Dexamethasone in Patients Hospitalized with COVID-19: Whether, When and to Whom
por: Calzetta, Luigino, et al.
Publicado: (2021)

The Impact of Corticosteroids on Human Airway Smooth Muscle Contractility and Airway Hyperresponsiveness: A Systematic Review
por: Calzetta, Luigino, et al.
Publicado: (2022)

Muscarinic receptor antagonists and airway inflammation: A systematic review on pharmacological models
por: Calzetta, Luigino, et al.
Publicado: (2022)

Stem Cell-Based Regenerative Therapy and Derived Products in COPD: A Systematic Review and Meta-Analysis
por: Calzetta, Luigino, et al.
Publicado: (2022)

The Impact of Muscarinic Receptor Antagonists on Airway Inflammation: A Systematic Review
por: Calzetta, Luigino, et al.
Publicado: (2021)

The BNT162b2 mRNA COVID-19 Vaccine Increases the Contractile Sensitivity to Histamine and Parasympathetic Activation in a Human Ex Vivo Model of Severe Eosinophilic Asthma
por: Calzetta, Luigino, et al.
Publicado: (2023)

Sex differences in adult asthma and COPD therapy: a systematic review
por: Rogliani, Paola, et al.
Publicado: (2022)

Experimental Glucocorticoid Receptor Agonists for the Treatment of Asthma: A Systematic Review
por: Rogliani, Paola, et al.
Publicado: (2020)

Severe Asthma and Biological Therapy: When, Which, and for Whom
por: Rogliani, Paola, et al.
Publicado: (2019)

Factors Influencing the Efficacy of COVID-19 Vaccines: A Quantitative Synthesis of Phase III Trials
por: Calzetta, Luigino, et al.
Publicado: (2021)

Drug interaction and chronic obstructive respiratory disorders
por: Rogliani, Paola, et al.
Publicado: (2020)

Beclomethasone dipropionate and sodium cromoglycate protect against airway hyperresponsiveness in a human ex vivo model of cow's milk aspiration
por: Ritondo, Beatrice Ludovica, et al.
Publicado: (2020)

Detection of Small Airway Dysfunction in Asymptomatic Smokers with Preserved Spirometry: The Value of the Impulse Oscillometry System
por: Pisi, Roberta, et al.
Publicado: (2021)

Potential Drawbacks of ICS/LABA/LAMA Triple Fixed-Dose Combination Therapy in the Treatment of Asthma: A Quantitative Synthesis of Safety Profile
por: Rogliani, Paola, et al.
Publicado: (2022)

Anthelminthic medicinal plants in veterinary ethnopharmacology: A network meta-analysis following the PRISMA-P and PROSPERO recommendations
por: Calzetta, Luigino, et al.
Publicado: (2020)

Detection of Small Airway Dysfunction in Asthmatic Patients by Spirometry and Impulse Oscillometry System
por: Pisi, Roberta, et al.
Publicado: (2023)

SARS-CoV-2 Neutralizing Antibodies: A Network Meta-Analysis across Vaccines
por: Rogliani, Paola, et al.
Publicado: (2021)

The impact of long-acting muscarinic antagonists on mucus hypersecretion and cough in chronic obstructive pulmonary disease: a systematic review
por: Calzetta, Luigino, et al.
Publicado: (2022)

Letter to the Editor Regarding “Clinical Remission in Severe Asthma: A Pooled Post Hoc Analysis of the Patient Journey with Benralizumab”
por: Calzetta, Luigino, et al.
Publicado: (2022)

Clinical manifestations of a new alpha‐1 antitrypsin genetic variant: Q0parma
por: Aiello, Marina, et al.
Publicado: (2022)

Clinical Interpretation of Efficacy Outcomes in Pharmacological Studies on Triple Fixed-Dose Combination Therapy for Uncontrolled Asthma: Assessment of IRIDIUM and ARGON Studies
por: Rogliani, Paola, et al.
Publicado: (2022)

An Impairment in Resting and Exertional Breathing Pattern May Occur in Long-COVID Patients with Normal Spirometry and Unexplained Dyspnoea
por: Frizzelli, Annalisa, et al.
Publicado: (2022)

Pharmacogenomic Response of Inhaled Corticosteroids for the Treatment of Asthma: Considerations for Therapy
por: Cazzola, Mario, et al.
Publicado: (2020)

Strength of association between comorbidities and asthma: a meta-analysis
por: Rogliani, Paola, et al.
Publicado: (2023)

Mortality in ETHOS: A Question of “Power”
por: Rogliani, Paola, et al.
Publicado: (2021)

Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis
por: Rogliani, Paola, et al.
Publicado: (2019)

What happens to people’s lungs when they get coronavirus disease 2019?
por: Frizzelli, Annalisa, et al.
Publicado: (2020)

Dysfunction of small airways and prevalence, airway responsiveness and inflammation in asthma: much more than small particle size of pet animal allergens
por: Liccardi, Gennaro, et al.
Publicado: (2016)

Long-Acting Muscarinic Antagonists Under Investigational to Treat Chronic Obstructive Pulmonary Disease
por: Ora, Josuel, et al.
Publicado: (2020)

Gender-related Responsiveness to the Pharmacological Treatment of COPD: A First Step Towards the Personalized Medicine
por: Calzetta, Luigino, et al.
Publicado: (2017)

Beclomethasone/Formoterol in Extra-Fine Formulation Improves Small Airway Dysfunction in COPD Patients
por: Pisi, Roberta, et al.
Publicado: (2021)

Is the risk of developing atopic sensitization and bronchial asthma in animal laboratory workers preventable in well-defined susceptible individuals?
por: Liccardi, Gennaro, et al.
Publicado: (2017)

Pharmacological investigation on the anti-oxidant and anti-inflammatory activity of N-acetylcysteine in an ex vivo model of COPD exacerbation
por: Cazzola, Mario, et al.
Publicado: (2017)

Pharmacological management of COVID-19 patients with ARDS (CARDS): A narrative review
por: Matera, Maria Gabriella, et al.
Publicado: (2020)

Triple Therapy Versus Dual Bronchodilation and Inhaled Corticosteroids/Long-Acting β-Agonists in COPD: Accumulating Evidence from Network Meta-Analyses
por: Cazzola, Mario, et al.
Publicado: (2019)

Optimizing the Development Strategy of Combination Therapy in Respiratory Medicine: From Isolated Airways to Patients
por: Calzetta, Luigino, et al.
Publicado: (2019)

Editorial overview: Respiratory: Pulmonary pharmacology–The emergence of new treatments in pulmonary medicine is finally providing real therapeutic perspectives
por: Cazzola, Mario, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_6stv8gchiftqdi2a7hccelo5h3