GJA1/CX43 High Expression Levels in the Cervical Spinal Cord of ALS Patients Correlate to Microglia-Mediated Neuroinflammatory Profile

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting motoneurons (MNs) with a fatal outcome. The typical degeneration of cortico-spinal, spinal, and bulbar MNs, observed in post-mortem biopsies, is associated with the activation of neuroimmune cells. GJA1, a memb...

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Detalles Bibliográficos
Autores principales: Vicario, Nunzio, Castrogiovanni, Paola, Imbesi, Rosa, Giallongo, Sebastiano, Mannino, Giuliana, Furno, Debora Lo, Giuffrida, Rosario, Zappalà, Agata, Li Volti, Giovanni, Tibullo, Daniele, Di Rosa, Michelino, Parenti, Rosalba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496195/
https://www.ncbi.nlm.nih.gov/pubmed/36140348
http://dx.doi.org/10.3390/biomedicines10092246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496195/
https://www.ncbi.nlm.nih.gov/pubmed/36140348
http://dx.doi.org/10.3390/biomedicines10092246

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