Novel 5-Nitrofuran-Tagged Imidazo-Fused Azines and Azoles Amenable by the Groebke–Blackburn–Bienaymé Multicomponent Reaction: Activity Profile against ESKAPE Pathogens and Mycobacteria

A chemically diverse set of 13 5-nitrofuran-tagged heterocyclic compounds has been prepared via the Groebke–Blackburn–Bienaymé multicomponent reaction. The testing of these compounds against the so-called ESKAPE panel of pathogens identified an apparent lead compound—N-cyclohexyl-2-(5-nitrofuran-2-y...

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Detalles Bibliográficos
Autores principales: Sapegin, Alexander, Rogacheva, Elizaveta, Kraeva, Lyudmila, Gureev, Maxim, Dogonadze, Marine, Vinogradova, Tatiana, Yablonsky, Petr, Balalaie, Saeed, Baykov, Sergey V., Krasavin, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496245/
https://www.ncbi.nlm.nih.gov/pubmed/36140307
http://dx.doi.org/10.3390/biomedicines10092203

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