Chagas Disease Megaesophagus Patients Carrying Variant MRPS18B P260A Display Nitro-Oxidative Stress and Mitochondrial Dysfunction in Response to IFN-γ Stimulus

Chagas disease (CD), caused by the protozoan parasite Trypanosoma cruzi, affects 8 million people, and around 1/3 develop chronic cardiac (CCC) or digestive disease (megaesophagus/megacolon), while the majority remain asymptomatic, in the indeterminate form of Chagas disease (ASY). Most CCC cases in...

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Detalles Bibliográficos
Autores principales: Silva, Karla Deysiree Alcântara, Nunes, João Paulo Silva, Andrieux, Pauline, Brochet, Pauline, Almeida, Rafael Ribeiro, Kuramoto Takara, Andréia Cristina Kazue, Pereira, Natalia Bueno, Abel, Laurent, Cobat, Aurelie, Zaniratto, Ricardo Costa Fernandes, Levy, Débora, Bydlowski, Sergio Paulo, Cecconello, Ivan, Seguro, Francisco Carlos Bernal da Costa, Kalil, Jorge, Chevillard, Christophe, Cunha-Neto, Edecio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496350/
https://www.ncbi.nlm.nih.gov/pubmed/36140315
http://dx.doi.org/10.3390/biomedicines10092215

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