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Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis

Discoidin domain receptor 1 (DDR1) is a collagen receptor that belongs to the receptor tyrosine kinase family. We have previously shown that DDR1 plays a crucial role during bone development, resulting in dwarfism and a short stature in osteoblast-specific knockout mice (OKO mice). However, the deta...

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Detalles Bibliográficos
Autores principales: Chou, Hsin-Chiao, Lin, Sung-Yen, Chou, Liang-Yin, Ho, Mei-Ling, Chuang, Shu-Chun, Cheng, Tsung-Lin, Kang, Lin, Lin, Yi-Shan, Wang, Yan-Hsiung, Wei, Chun-Wang, Chen, Chung-Hwan, Wang, Chau-Zen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496360/
https://www.ncbi.nlm.nih.gov/pubmed/36140274
http://dx.doi.org/10.3390/biomedicines10092173