The Role of Disordered Regions in Orchestrating the Properties of Multidomain Proteins: The SARS-CoV-2 Nucleocapsid Protein and Its Interaction with Enoxaparin

Novel and efficient strategies need to be developed to interfere with the SARS-CoV-2 virus. One of the most promising pharmaceutical targets is the nucleocapsid protein (N), responsible for genomic RNA packaging. N is composed of two folded domains and three intrinsically disordered regions (IDRs)....

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Detalles Bibliográficos
Autores principales: Schiavina, Marco, Pontoriero, Letizia, Tagliaferro, Giuseppe, Pierattelli, Roberta, Felli, Isabella C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496478/
https://www.ncbi.nlm.nih.gov/pubmed/36139141
http://dx.doi.org/10.3390/biom12091302

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