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Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study

INTRODUCTION: Chronic pain, nocturnal cramps, and sleep alterations are prevalent symptoms and signals in Charcot-Marie-Tooth disease patients. Sleep and pain are bidirectionally related and physical therapy can improve the binomial sleep and pain/nocturnal cramps. Therefore, we hypothesized that th...

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Autores principales: Souza, Cynthia Coelho, Vallim, Julia Ribeiro da Silva, Neves, Eduardo Luis de Aquino, Nunes, Paula Santos, Costa, Iandra Maria Pinheiro de França, Barreto, Lidiane Carine Lima Santos, Garcez, Catarina Andrade, Araujo, Adriano Antunes de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Association of Sleep and Latin American Federation of Sleep 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496488/
https://www.ncbi.nlm.nih.gov/pubmed/36158726
http://dx.doi.org/10.5935/1984-0063.20220058
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author Souza, Cynthia Coelho
Vallim, Julia Ribeiro da Silva
Neves, Eduardo Luis de Aquino
Nunes, Paula Santos
Costa, Iandra Maria Pinheiro de França
Barreto, Lidiane Carine Lima Santos
Garcez, Catarina Andrade
Araujo, Adriano Antunes de Souza
author_facet Souza, Cynthia Coelho
Vallim, Julia Ribeiro da Silva
Neves, Eduardo Luis de Aquino
Nunes, Paula Santos
Costa, Iandra Maria Pinheiro de França
Barreto, Lidiane Carine Lima Santos
Garcez, Catarina Andrade
Araujo, Adriano Antunes de Souza
author_sort Souza, Cynthia Coelho
collection PubMed
description INTRODUCTION: Chronic pain, nocturnal cramps, and sleep alterations are prevalent symptoms and signals in Charcot-Marie-Tooth disease patients. Sleep and pain are bidirectionally related and physical therapy can improve the binomial sleep and pain/nocturnal cramps. Therefore, we hypothesized that the application of a specific physical therapy program for Charcot-Marie-Tooth disease would improve sleep quality, pain perception, and nocturnal cramps. MATERIAL AND METHODS: A non-randomized controlled study that included 9 Charcot-Marie-Tooth disease patients (intervention group - physical therapy program) and 8 controls (active control group - booklet on sleep hygiene). The intervention lasted 8 weeks, three sessions per week. The effects were evaluated ten days before (baseline) and ten days after the intervention (post). Our primary outcome was sleep quality (subjective and objective, assessed by Pittsburgh sleep quality index and actigraphy, respectively); and secondary outcomes were pain perception (brief pain inventory) and nocturnal cramps (self-report). RESULTS: The program was able to improve the subjective sleep quality (p=0.005) and nocturnal cramps (p<0.001) but had no effect on actigraphy data (p>0.05) neither on pain perception (p>0.05). CONCLUSION: Our initial hypothesis was partially corroborated: the improvement in subjective quality of sleep and nocturnal cramps is already beneficial for the health promotion of the volunteers in this study affected by the disease. Our findings may serve as a basis for future research to develop a program focused on the treatment of analgesia, which can improve pain perception and alter the objective quality of sleep.
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spelling pubmed-94964882022-09-23 Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study Souza, Cynthia Coelho Vallim, Julia Ribeiro da Silva Neves, Eduardo Luis de Aquino Nunes, Paula Santos Costa, Iandra Maria Pinheiro de França Barreto, Lidiane Carine Lima Santos Garcez, Catarina Andrade Araujo, Adriano Antunes de Souza Sleep Sci Original Articles INTRODUCTION: Chronic pain, nocturnal cramps, and sleep alterations are prevalent symptoms and signals in Charcot-Marie-Tooth disease patients. Sleep and pain are bidirectionally related and physical therapy can improve the binomial sleep and pain/nocturnal cramps. Therefore, we hypothesized that the application of a specific physical therapy program for Charcot-Marie-Tooth disease would improve sleep quality, pain perception, and nocturnal cramps. MATERIAL AND METHODS: A non-randomized controlled study that included 9 Charcot-Marie-Tooth disease patients (intervention group - physical therapy program) and 8 controls (active control group - booklet on sleep hygiene). The intervention lasted 8 weeks, three sessions per week. The effects were evaluated ten days before (baseline) and ten days after the intervention (post). Our primary outcome was sleep quality (subjective and objective, assessed by Pittsburgh sleep quality index and actigraphy, respectively); and secondary outcomes were pain perception (brief pain inventory) and nocturnal cramps (self-report). RESULTS: The program was able to improve the subjective sleep quality (p=0.005) and nocturnal cramps (p<0.001) but had no effect on actigraphy data (p>0.05) neither on pain perception (p>0.05). CONCLUSION: Our initial hypothesis was partially corroborated: the improvement in subjective quality of sleep and nocturnal cramps is already beneficial for the health promotion of the volunteers in this study affected by the disease. Our findings may serve as a basis for future research to develop a program focused on the treatment of analgesia, which can improve pain perception and alter the objective quality of sleep. Brazilian Association of Sleep and Latin American Federation of Sleep 2022 /pmc/articles/PMC9496488/ /pubmed/36158726 http://dx.doi.org/10.5935/1984-0063.20220058 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Souza, Cynthia Coelho
Vallim, Julia Ribeiro da Silva
Neves, Eduardo Luis de Aquino
Nunes, Paula Santos
Costa, Iandra Maria Pinheiro de França
Barreto, Lidiane Carine Lima Santos
Garcez, Catarina Andrade
Araujo, Adriano Antunes de Souza
Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
title Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
title_full Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
title_fullStr Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
title_full_unstemmed Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
title_short Effectiveness of a specific physical therapy program for Charcot-Marie-Tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
title_sort effectiveness of a specific physical therapy program for charcot-marie-tooth on sleep quality, pain perception, and nocturnal cramps: a pilot study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496488/
https://www.ncbi.nlm.nih.gov/pubmed/36158726
http://dx.doi.org/10.5935/1984-0063.20220058
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