Cargando…

t(6)A and ms(2)t(6)A Modified Nucleosides in Serum and Urine as Strong Candidate Biomarkers of COVID-19 Infection and Severity

SARS-CoV-2 infection alters cellular RNA content. Cellular RNAs are chemically modified and eventually degraded, depositing modified nucleosides into extracellular fluids such as serum and urine. Here we searched for COVID-19-specific changes in modified nucleoside levels contained in serum and urin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nagayoshi, Yu, Nishiguchi, Kayo, Yamamura, Ryosuke, Chujo, Takeshi, Oshiumi, Hiroyuki, Nagata, Hiroko, Kaneko, Hitomi, Yamamoto, Keiichi, Nakata, Hirotomo, Sakakida, Korin, Kunisawa, Akihiro, Adachi, Masataka, Kakizoe, Yutaka, Mizobe, Takanori, Kuratsu, Jun-ichi, Shimada, Shinya, Nakamori, Yasushi, Matsuoka, Masao, Mukoyama, Masashi, Wei, Fan-Yan, Tomizawa, Kazuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496545/ https://www.ncbi.nlm.nih.gov/pubmed/36139072 http://dx.doi.org/10.3390/biom12091233

Ejemplares similares

Export of RNA-derived modified nucleosides by equilibrative nucleoside transporters defines the magnitude of autophagy response and Zika virus replication
por: Shi, Sheng-Lan, et al.
Publicado: (2021)

A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats
por: Iwata, Yasunobu, et al.
Publicado: (2023)

Extracellular N(6)-isopentenyladenosine (i(6)A) addition induces cotranscriptional i(6)A incorporation into ribosomal RNAs
por: Yakita, Maya, et al.
Publicado: (2022)

Human transfer RNA modopathies: diseases caused by aberrations in transfer RNA modifications
por: Chujo, Takeshi, et al.
Publicado: (2021)

Efficacy of continuous erythropoietin receptor activator for end-stage renal disease patients with renal anemia before and after peritoneal dialysis initiation
por: Fujimoto, Daisuke, et al.
Publicado: (2020)

Cooperative methylation of human tRNA(3)(Lys) at positions A58 and U54 drives the early and late steps of HIV-1 replication
por: Fukuda, Hiroyuki, et al.
Publicado: (2021)

Palladium‐Catalyzed Aryl Amination Reactions of 6‐Bromo‐ and 6‐Chloropurine Nucleosides
por: Thomson, Paul F., et al.
Publicado: (2010)

Response to Stimulations Inducing Circadian Rhythm in Human Induced Pluripotent Stem Cells
por: Kaneko, Hitomi, et al.
Publicado: (2020)

Enzymatic synthesis and phosphorolysis of 4(2)-thioxo- and 6(5)-azapyrimidine nucleosides by E. coli nucleoside phosphorylases
por: Stepchenko, Vladimir A, et al.
Publicado: (2016)

Cladribine Analogues via O(6)-(Benzotriazolyl) Derivatives of Guanine Nucleosides
por: Satishkumar, Sakilam, et al.
Publicado: (2015)

Resistance to chemical carcinogenesis induction via a dampened inflammatory response in naked mole-rats
por: Oka, Kaori, et al.
Publicado: (2022)

6-Methyl-7-deazapurine nucleoside analogues as broad-spectrum antikinetoplastid agents
por: Lin, Cai, et al.
Publicado: (2021)

Enzymatic deamination of the epigenetic nucleoside N(6)-methyladenosine regulates gene expression
por: Jiang, Zhuoran, et al.
Publicado: (2021)

Specificity in the biosynthesis of the universal tRNA nucleoside N(6)-threonylcarbamoyl adenosine (t(6)A)—TsaD is the gatekeeper
por: Swinehart, William, et al.
Publicado: (2020)

Synthesis of 3-fluoro-6-S-(2-S-pyridyl) nucleosides as potential lead cytostatic agents
por: Tsoukala, Evangelia, et al.
Publicado: (2010)

Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters
por: Johnson, Zachary Lee, et al.
Publicado: (2014)

Ablation of Myeloid Cell MRP8 Ameliorates Nephrotoxic Serum-induced Glomerulonephritis by Affecting Macrophage Characterization through Intraglomerular Crosstalk
por: Hata, Yusuke, et al.
Publicado: (2020)

Cdk5rap1-mediated 2-methylthio-N(6)-isopentenyladenosine modification is absent from nuclear-derived RNA species
por: Fakruddin, Md., et al.
Publicado: (2017)

Immune‐suppressive effects of interleukin‐6 on T‐cell‐mediated anti‐tumor immunity
por: Tsukamoto, Hirotake, et al.
Publicado: (2017)

Standing magnetic resonance imaging of distal phalanx fractures in 6 cases of Thoroughbred racehorse
por: MIZOBE, Fumiaki, et al.
Publicado: (2019)

2-Methylthio Conversion of N6-Isopentenyladenosine in Mitochondrial tRNAs by CDK5RAP1 Promotes the Maintenance of Glioma-Initiating Cells
por: Yamamoto, Takahiro, et al.
Publicado: (2019)

6-methylmercaptopurine riboside, a thiopurine nucleoside with antiviral activity against canine distemper virus in vitro
por: de Carvalho, Otávio Valério, et al.
Publicado: (2017)

Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents
por: Ikejiri, Masahiro, et al.
Publicado: (2007)

α-Tocopherol phosphate as a photosensitizer in the reaction of nucleosides with UV light: formation of 5,6-dihydrothymidine
por: Suzuki, Toshinori, et al.
Publicado: (2022)

Sirtuin 7 Deficiency Ameliorates Cisplatin-induced Acute Kidney Injury Through Regulation of the Inflammatory Response
por: Miyasato, Yoshikazu, et al.
Publicado: (2018)

Strained Conformations of Nucleosides in Active Sites of Nucleoside Phosphorylases
por: Il’icheva, Irina A., et al.
Publicado: (2020)

Emerging roles of metabolites of ω3 and ω6 essential fatty acids in the control of intestinal inflammation
por: Nagatake, Takahiro, et al.
Publicado: (2019)

Nucleoside Sensing
por: Fokkens, Michael, et al.
Publicado: (2006)

Decreased erythrocyte nucleoside transport and hENT1 transporter expression in glucose 6-phosphate dehydrogenase deficiency
por: Al-Ansari, Mohammad, et al.
Publicado: (2015)

Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab
por: Araki, Manabu, et al.
Publicado: (2012)

CDKAL1 Drives the Maintenance of Cancer Stem‐Like Cells by Assembling the eIF4F Translation Initiation Complex
por: Huang, Rongsheng, et al.
Publicado: (2023)

Cell-Penetrating Peptide as a Means of Directing the Differentiation of Induced Pluripotent Stem Cells
por: Kaitsuka, Taku, et al.
Publicado: (2015)

The nucleoside analog clitocine is a potent and efficacious readthrough agent
por: Friesen, Westley J., et al.
Publicado: (2017)

Evolving specificity of tRNA 3-methyl-cytidine-32 (m(3)C32) modification: a subset of tRNAs(Ser) requires N(6)-isopentenylation of A37
por: Arimbasseri, Aneeshkumar G., et al.
Publicado: (2016)

Liddle’s-like syndrome associated with nephrotic syndrome secondary to membranous nephropathy: the first case report
por: Yamaguchi, Eriko, et al.
Publicado: (2018)

Suppression of Indoxyl Sulfate Accumulation Reduces Renal Fibrosis in Sulfotransferase 1a1-Deficient Mice
por: Hou, Huixian, et al.
Publicado: (2023)

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit
por: Heib, Anna, et al.
Publicado: (2019)

Review on fluorinated nucleoside/non-nucleoside FDA-approved antiviral drugs
por: Ismail, Magda M. F., et al.
Publicado: (2022)

Lack of tRNA-i6A modification causes mitochondrial-like metabolic deficiency in S. pombe by limiting activity of cytosolic tRNA(Tyr), not mito-tRNA
por: Lamichhane, Tek N., et al.
Publicado: (2016)

The Chemistry of Nucleosides and Nucleotides
por: Mautner, Henry G.
Publicado: (1963)

Cannot write session to /tmp/vufind_sessions/sess_r75a8qe5htr4j914ul86slvr4t