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Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours

This work introduces a microwave-based system able to detect tumours in breast phantoms in a non-invasive way. The data acquisition system is composed of a hardware system which involves high-frequency components (antennas, switches and cables), a microcontroller, a vector network analyser used as m...

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Autores principales: Blanco-Angulo, Carolina, Martínez-Lozano, Andrea, Gutiérrez-Mazón, Roberto, Juan, Carlos G., García-Martínez, Héctor, Arias-Rodríguez, Julia, Sabater-Navarro, José M., Ávila-Navarro, Ernesto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496561/
https://www.ncbi.nlm.nih.gov/pubmed/36140137
http://dx.doi.org/10.3390/bios12090752
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author Blanco-Angulo, Carolina
Martínez-Lozano, Andrea
Gutiérrez-Mazón, Roberto
Juan, Carlos G.
García-Martínez, Héctor
Arias-Rodríguez, Julia
Sabater-Navarro, José M.
Ávila-Navarro, Ernesto
author_facet Blanco-Angulo, Carolina
Martínez-Lozano, Andrea
Gutiérrez-Mazón, Roberto
Juan, Carlos G.
García-Martínez, Héctor
Arias-Rodríguez, Julia
Sabater-Navarro, José M.
Ávila-Navarro, Ernesto
author_sort Blanco-Angulo, Carolina
collection PubMed
description This work introduces a microwave-based system able to detect tumours in breast phantoms in a non-invasive way. The data acquisition system is composed of a hardware system which involves high-frequency components (antennas, switches and cables), a microcontroller, a vector network analyser used as measurement instrument and a computer devoted to the control and automation of the operation of the system. Concerning the software system, the computer runs a Python script which is in charge of mastering and automatising all the required stages for the data acquisition, from initialisation of the hardware system to performing and saving the measurements. We also report on the design of the high-performance broadband antenna used to carry out the measurements, as well as on the algorithm employed to build the final medical images, based on an adapted version of the so-called Improved Delay-and-Sum (IDAS) algorithm improved by a Hamming window filter and averaging preprocessing. The calibration and start-up of the system are also described. The experimental validation includes the use of different tumour models with different dielectric properties inside the breast phantom. The results show promising tumour detection capabilities, even when there is low dielectric contrast between the tumoural and healthy tissues, as is the usual case for dense breasts in young women.
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spelling pubmed-94965612022-09-23 Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours Blanco-Angulo, Carolina Martínez-Lozano, Andrea Gutiérrez-Mazón, Roberto Juan, Carlos G. García-Martínez, Héctor Arias-Rodríguez, Julia Sabater-Navarro, José M. Ávila-Navarro, Ernesto Biosensors (Basel) Article This work introduces a microwave-based system able to detect tumours in breast phantoms in a non-invasive way. The data acquisition system is composed of a hardware system which involves high-frequency components (antennas, switches and cables), a microcontroller, a vector network analyser used as measurement instrument and a computer devoted to the control and automation of the operation of the system. Concerning the software system, the computer runs a Python script which is in charge of mastering and automatising all the required stages for the data acquisition, from initialisation of the hardware system to performing and saving the measurements. We also report on the design of the high-performance broadband antenna used to carry out the measurements, as well as on the algorithm employed to build the final medical images, based on an adapted version of the so-called Improved Delay-and-Sum (IDAS) algorithm improved by a Hamming window filter and averaging preprocessing. The calibration and start-up of the system are also described. The experimental validation includes the use of different tumour models with different dielectric properties inside the breast phantom. The results show promising tumour detection capabilities, even when there is low dielectric contrast between the tumoural and healthy tissues, as is the usual case for dense breasts in young women. MDPI 2022-09-12 /pmc/articles/PMC9496561/ /pubmed/36140137 http://dx.doi.org/10.3390/bios12090752 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Blanco-Angulo, Carolina
Martínez-Lozano, Andrea
Gutiérrez-Mazón, Roberto
Juan, Carlos G.
García-Martínez, Héctor
Arias-Rodríguez, Julia
Sabater-Navarro, José M.
Ávila-Navarro, Ernesto
Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours
title Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours
title_full Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours
title_fullStr Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours
title_full_unstemmed Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours
title_short Non-Invasive Microwave-Based Imaging System for Early Detection of Breast Tumours
title_sort non-invasive microwave-based imaging system for early detection of breast tumours
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496561/
https://www.ncbi.nlm.nih.gov/pubmed/36140137
http://dx.doi.org/10.3390/bios12090752
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