The Pathological Mechanisms of Hearing Loss Caused by KCNQ1 and KCNQ4 Variants

Deafness-associated genes KCNQ1 (also associated with heart diseases) and KCNQ4 (only associated with hearing loss) encode the homotetrameric voltage-gated potassium ion channels Kv7.1 and Kv7.4, respectively. To date, over 700 KCNQ1 and over 70 KCNQ4 variants have been identified in patients. The v...

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Detalles Bibliográficos
Autor principal: Homma, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496569/
https://www.ncbi.nlm.nih.gov/pubmed/36140355
http://dx.doi.org/10.3390/biomedicines10092254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496569/
https://www.ncbi.nlm.nih.gov/pubmed/36140355
http://dx.doi.org/10.3390/biomedicines10092254

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