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Co-administration of MDR1 and BCRP or EGFR/PI3K inhibitors overcomes lenvatinib resistance in hepatocellular carcinoma

Lenvatinib is the first-line treatment for hepatocellular carcinoma (HCC), the most common type of primary liver cancer; however, some patients become refractory to lenvatinib. The underlying mechanism of lenvatinib resistance (LR) in patients with advanced HCC remains unclear. We focused on explori...

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Detalles Bibliográficos
Autores principales:	Sun, Dawei, Liu, Juan, Wang, Yunfang, Dong, Jiahong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496645/ https://www.ncbi.nlm.nih.gov/pubmed/36158676 http://dx.doi.org/10.3389/fonc.2022.944537

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