Intraparenchymal Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Report

Marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (MALT) type, which is primary to the central nervous system (CNS), is a rare lesion, with those originating within the parenchyma even more so. We present the case of a 64-year-old male with weakness in the left hand and foca...

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Detalles Bibliográficos
Autores principales: Laghaei Farimani, Pedram, Karthikeyan, Vishwathsen, Fatehi, Mostafa, Levine, Adrian, Slack, Graham W, Mackenzie, Ian R, Haw, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496647/
https://www.ncbi.nlm.nih.gov/pubmed/36158354
http://dx.doi.org/10.7759/cureus.28301
Descripción
Sumario:Marginal zone B-cell lymphoma (MZBCL) of mucosa-associated lymphoid tissue (MALT) type, which is primary to the central nervous system (CNS), is a rare lesion, with those originating within the parenchyma even more so. We present the case of a 64-year-old male with weakness in the left hand and focal motor seizures of his arm, who was found to have a right frontal intraparenchymal lesion. Following resection, histopathological and immunohistochemical evaluations were completed, leading to a diagnosis of a primary CNS MZBCL of MALT type in the context of a negative workup of systemic disease. Neuroimaging, histopathological, and immunohistochemical findings, as well as a comprehensive literature review of similar cases, are discussed.

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