Generation and Characterization of a Novel Angelman Syndrome Mouse Model with a Full Deletion of the Ube3a Gene

Angelman syndrome (AS) is a neurodevelopmental disorder caused by deficits in maternally inherited UBE3A. The disease is characterized by intellectual disability, impaired motor skills, and behavioral deficits, including increased anxiety and autism spectrum disorder features. The mouse models used...

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Detalles Bibliográficos
Autores principales: Syding, Linn Amanda, Kubik-Zahorodna, Agnieszka, Nickl, Petr, Novosadova, Vendula, Kopkanova, Jana, Kasparek, Petr, Prochazka, Jan, Sedlacek, Radislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496699/
https://www.ncbi.nlm.nih.gov/pubmed/36139390
http://dx.doi.org/10.3390/cells11182815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496699/
https://www.ncbi.nlm.nih.gov/pubmed/36139390
http://dx.doi.org/10.3390/cells11182815

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