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Hashimoto Encephalopathy—Still More Questions than Answers
The normal function of the nervous system is conditioned by the undisturbed function of the thyroid gland and its hormones. Comprehensive clinical manifestations, including neurological disorders in Hashimoto’s thyroiditis, have long been understood and, in recent years, attention has been paid to n...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496753/ https://www.ncbi.nlm.nih.gov/pubmed/36139446 http://dx.doi.org/10.3390/cells11182873 |
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author | Waliszewska-Prosół, Marta Ejma, Maria |
author_facet | Waliszewska-Prosół, Marta Ejma, Maria |
author_sort | Waliszewska-Prosół, Marta |
collection | PubMed |
description | The normal function of the nervous system is conditioned by the undisturbed function of the thyroid gland and its hormones. Comprehensive clinical manifestations, including neurological disorders in Hashimoto’s thyroiditis, have long been understood and, in recent years, attention has been paid to neurological symptoms in euthyroid patients. Hashimoto encephalopathy is a controversial and poorly understood disease entity and the pathogenesis of the condition remains unclear. We still derive our understanding of this condition from case reports, but on the basis of these, a clear clinical picture of this entity can be proposed. Based on a review of the recent literature, the authors present the current view on the subject, discuss controversies and questions that still remain unanswered, as well as ongoing research in this area and the results of our own work in patients with Hashimoto’s thyroiditis. |
format | Online Article Text |
id | pubmed-9496753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94967532022-09-23 Hashimoto Encephalopathy—Still More Questions than Answers Waliszewska-Prosół, Marta Ejma, Maria Cells Review The normal function of the nervous system is conditioned by the undisturbed function of the thyroid gland and its hormones. Comprehensive clinical manifestations, including neurological disorders in Hashimoto’s thyroiditis, have long been understood and, in recent years, attention has been paid to neurological symptoms in euthyroid patients. Hashimoto encephalopathy is a controversial and poorly understood disease entity and the pathogenesis of the condition remains unclear. We still derive our understanding of this condition from case reports, but on the basis of these, a clear clinical picture of this entity can be proposed. Based on a review of the recent literature, the authors present the current view on the subject, discuss controversies and questions that still remain unanswered, as well as ongoing research in this area and the results of our own work in patients with Hashimoto’s thyroiditis. MDPI 2022-09-14 /pmc/articles/PMC9496753/ /pubmed/36139446 http://dx.doi.org/10.3390/cells11182873 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Waliszewska-Prosół, Marta Ejma, Maria Hashimoto Encephalopathy—Still More Questions than Answers |
title | Hashimoto Encephalopathy—Still More Questions than Answers |
title_full | Hashimoto Encephalopathy—Still More Questions than Answers |
title_fullStr | Hashimoto Encephalopathy—Still More Questions than Answers |
title_full_unstemmed | Hashimoto Encephalopathy—Still More Questions than Answers |
title_short | Hashimoto Encephalopathy—Still More Questions than Answers |
title_sort | hashimoto encephalopathy—still more questions than answers |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496753/ https://www.ncbi.nlm.nih.gov/pubmed/36139446 http://dx.doi.org/10.3390/cells11182873 |
work_keys_str_mv | AT waliszewskaprosołmarta hashimotoencephalopathystillmorequestionsthananswers AT ejmamaria hashimotoencephalopathystillmorequestionsthananswers |