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Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients

Microvascular decompression (MVD) is the only etiological technique for the treatment of trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of age, the elderly population is thought to be more prone to have a higher rate of surgical complication, morbidity, and...

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Autores principales: Menna, Grazia, Rapisarda, Alessandro, Izzo, Alessandro, D’Ercole, Manuela, D’Alessandris, Quintino Giorgio, Olivi, Alessandro, Montano, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496765/
https://www.ncbi.nlm.nih.gov/pubmed/36138952
http://dx.doi.org/10.3390/brainsci12091216
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author Menna, Grazia
Rapisarda, Alessandro
Izzo, Alessandro
D’Ercole, Manuela
D’Alessandris, Quintino Giorgio
Olivi, Alessandro
Montano, Nicola
author_facet Menna, Grazia
Rapisarda, Alessandro
Izzo, Alessandro
D’Ercole, Manuela
D’Alessandris, Quintino Giorgio
Olivi, Alessandro
Montano, Nicola
author_sort Menna, Grazia
collection PubMed
description Microvascular decompression (MVD) is the only etiological technique for the treatment of trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of age, the elderly population is thought to be more prone to have a higher rate of surgical complication, morbidity, and mortality. The main objective of our single-center, retrospective study was to analyze the surgical and clinical outcomes of MVD in TN elderly patients. From a surgical series of patients with TN who had undergone MVD from April 2018 to April 2022, 76 patients who matched the inclusion criteria were divided into two groups: twenty-five (32.9%) patients were older than 65 years and included in the elderly group, while the remaining fifty-one (61.1%) patients were below 65 years included in the non-elderly one. There were no differences between the groups in terms of acute pain relief (APR), Barrow Neurological Index (BNI) at follow-up, complications, and recurrence rate. In multivariate analysis (Cox proportional hazards regression analysis) the presence of an offending artery with nerve root distortion/indentation emerged as the only independent prognostic factor for pain-free survival (p = 0.0001). Our data endorse MVD as a safe and effective surgical procedure also for elderly patients with TN.
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spelling pubmed-94967652022-09-23 Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients Menna, Grazia Rapisarda, Alessandro Izzo, Alessandro D’Ercole, Manuela D’Alessandris, Quintino Giorgio Olivi, Alessandro Montano, Nicola Brain Sci Article Microvascular decompression (MVD) is the only etiological technique for the treatment of trigeminal neuralgia (TN). Whilst there is a consensus MVD is likely effective regardless of age, the elderly population is thought to be more prone to have a higher rate of surgical complication, morbidity, and mortality. The main objective of our single-center, retrospective study was to analyze the surgical and clinical outcomes of MVD in TN elderly patients. From a surgical series of patients with TN who had undergone MVD from April 2018 to April 2022, 76 patients who matched the inclusion criteria were divided into two groups: twenty-five (32.9%) patients were older than 65 years and included in the elderly group, while the remaining fifty-one (61.1%) patients were below 65 years included in the non-elderly one. There were no differences between the groups in terms of acute pain relief (APR), Barrow Neurological Index (BNI) at follow-up, complications, and recurrence rate. In multivariate analysis (Cox proportional hazards regression analysis) the presence of an offending artery with nerve root distortion/indentation emerged as the only independent prognostic factor for pain-free survival (p = 0.0001). Our data endorse MVD as a safe and effective surgical procedure also for elderly patients with TN. MDPI 2022-09-09 /pmc/articles/PMC9496765/ /pubmed/36138952 http://dx.doi.org/10.3390/brainsci12091216 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Menna, Grazia
Rapisarda, Alessandro
Izzo, Alessandro
D’Ercole, Manuela
D’Alessandris, Quintino Giorgio
Olivi, Alessandro
Montano, Nicola
Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
title Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
title_full Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
title_fullStr Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
title_full_unstemmed Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
title_short Surgical and Clinical Outcomes of Microvascular Decompression: A Comparative Study between Young and Elderly Patients
title_sort surgical and clinical outcomes of microvascular decompression: a comparative study between young and elderly patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496765/
https://www.ncbi.nlm.nih.gov/pubmed/36138952
http://dx.doi.org/10.3390/brainsci12091216
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