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A Selective Histone Deacetylase Inhibitor Induces Autophagy and Cell Death via SCNN1A Downregulation in Glioblastoma Cells

SIMPLE SUMMARY: Glioblastoma multiforme (GBM) patients have a poor prognosis. Recent literature has shown that GBM treatment is challenging, mainly due to the heterogeneity of GBM. Epigenetic deregulation by histone modifications is found in GBM. In this study, several pan- and specific histone deac...

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Detalles Bibliográficos
Autores principales: Chang, Hui Hua, Chang, Yao-Yuan, Tsai, Bing-Chen, Chen, Li-Jyun, Chang, An-Chi, Chuang, Jian-Ying, Gean, Po-Wu, Hsueh, Yuan-Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496778/
https://www.ncbi.nlm.nih.gov/pubmed/36139696
http://dx.doi.org/10.3390/cancers14184537