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IL-33 Alleviates Postoperative Cognitive Impairment by Inhibiting Hippocampal Inflammation and Upregulating Excitatory Synaptic Number in Aged Mice

Delayed neurocognitive recovery (dNCR), a postoperative complication that occurs in elderly patients, still lacks effective treatment. Interleukin-33 (IL-33) has been proved to modulate neuroinflammation and synaptic plasticity, among other effects, but the role of IL-33 in dNCR is not clear. We est...

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Detalles Bibliográficos
Autores principales: Li, Qi, Zhao, Yuqian, Shi, Chuanchuan, Song, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496788/
https://www.ncbi.nlm.nih.gov/pubmed/36138980
http://dx.doi.org/10.3390/brainsci12091244