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Targeting Mutant p53 for Cancer Treatment: Moving Closer to Clinical Use?
SIMPLE SUMMARY: Cancer is largely caused by genetic alterations such as mutations in a group of genes known as cancer driver genes. Many of the key advances in cancer treatment in recent years have involved blocking these driver genes using a new generation of anti-cancer drugs. Although p53 is the...
Autores principales: | Duffy, Michael J., Tang, Minhong, Rajaram, Subhasree, O’Grady, Shane, Crown, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496879/ https://www.ncbi.nlm.nih.gov/pubmed/36139658 http://dx.doi.org/10.3390/cancers14184499 |
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