Cargando…

Combined Focused Next-Generation Sequencing Assays to Guide Precision Oncology in Solid Tumors: A Retrospective Analysis from an Institutional Molecular Tumor Board

SIMPLE SUMMARY: The molecular characterization of tumor tissues has become essential to classify tumors, assess prognoses and optimize treatment. However, there is still no consensus about the use of molecular diagnostics broadly across tumor types due to costs and limited evidence for the actual be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tarawneh, Thomas S., Rodepeter, Fiona R., Teply-Szymanski, Julia, Ross, Petra, Koch, Vera, Thölken, Clemens, Schäfer, Jonas A., Gremke, Niklas, Mack, Hildegard I. D., Gold, Judith, Riera-Knorrenschild, Jorge, Wilhelm, Christian, Rinke, Anja, Middeke, Martin, Klemmer, Andreas, Romey, Marcel, Hattesohl, Akira, Jesinghaus, Moritz, Görg, Christian, Figiel, Jens, Chung, Ho-Ryun, Wündisch, Thomas, Neubauer, Andreas, Denkert, Carsten, Mack, Elisabeth K. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496918/ https://www.ncbi.nlm.nih.gov/pubmed/36139590 http://dx.doi.org/10.3390/cancers14184430

Ejemplares similares

A rational two-step approach to KRAS mutation testing in colorectal cancer using high resolution melting analysis and pyrosequencing
por: Mack, Elisabeth, et al.
Publicado: (2016)

Modulation of Autophagy-Like Processes by Tumor Viruses
por: Mack, Hildegard I. D., et al.
Publicado: (2012)

The Value of Contrast-Enhanced Ultrasound (CEUS) in the Detection of Perfusion Disturbances in Abdominal Wall Hernias Compared with Surgical and Histological Assessment
por: Safai Zadeh, Ehsan, et al.
Publicado: (2022)

Registered report: Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF
por: Bhargava, Ajay, et al.
Publicado: (2016)

Serum proteomics hint at an early T-cell response and modulation of SARS-CoV-2-related pathogenic pathways in COVID-19-ARDS treated with Ruxolitinib
por: Völkel, Sara, et al.
Publicado: (2023)

Intercostal Neurinoma: A Rare Cause of Persistent Thoracic Pain
por: Meyer, Christian, et al.
Publicado: (2014)

Frequency and Prognostic Significance of Intertumoural Heterogeneity in Multifocal Jejunoileal Neuroendocrine Tumours
por: Jesinghaus, Moritz, et al.
Publicado: (2022)

Ruxolitinib for the treatment of SARS-CoV-2 induced acute respiratory distress syndrome (ARDS)
por: Neubauer, Andreas, et al.
Publicado: (2020)

Water Channels Aquaporin 4 and -1 Expression in Subependymoma Depends on the Localization of the Tumors
por: Noell, Susan, et al.
Publicado: (2015)

Medical Treatment of Gastroenteropancreatic Neuroendocrine Tumors
por: Rinke, Anja, et al.
Publicado: (2012)

Hepatic perivascular epithelioid cell tumor (PEComa): contrast-enhanced ultrasound (CEUS) characteristics—a case report and literature review
por: Matrood, Sami, et al.
Publicado: (2023)

Prospective study on complications using different techniques for parotidectomy for benign tumors
por: Thölken, Rubens, et al.
Publicado: (2021)

Regulation of fatty acid desaturase- and immunity gene-expression by mbk-1/DYRK1A in Caenorhabditis elegans
por: Mack, Hildegard I. D., et al.
Publicado: (2022)

Acromegaly in a patient with a pulmonary neuroendocrine tumor: case report and review of current literature
por: Krug, Sebastian, et al.
Publicado: (2016)

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing
por: Mack, Elisabeth K.M., et al.
Publicado: (2019)

Emerging topics in C. elegans aging research: Transcriptional regulation, stress response and epigenetics
por: Denzel, Martin S., et al.
Publicado: (2018)

Transcutaneous B-mode ultrasound (TUS) and contrast-enhanced ultrasound (CEUS) pattern of mediastinal tumors: a pictorial essay
por: Zadeh, Ehsan Safai, et al.
Publicado: (2021)

Further Extension of Lifespan by Unc-43/CaMKII and Egl-8/PLCβ Mutations in Germline-Deficient Caenorhabditis elegans
por: Mack, Hildegard I. D., et al.
Publicado: (2022)

Selective targeting of tumor associated macrophages in different tumor models
por: Kakoschky, Bianca, et al.
Publicado: (2018)

Prevention and treatment of tumor lysis syndrome, and the efficacy and role of rasburicase
por: Alakel, Nael, et al.
Publicado: (2017)

Data interpretation raises risk for performance depression in broiler production
por: Lemme, Andreas, et al.
Publicado: (2021)

Diagnostic Accuracy and Post-Procedural Complications Associated with Ultrasound-Guided Core Needle Biopsy in the Preoperative Evaluation of Parotid Tumors
por: Jering, Monika, et al.
Publicado: (2021)

ALK(G1269A) mutation as a potential mechanism of acquired resistance to crizotinib in an ALK-rearranged inflammatory myofibroblastic tumor
por: Michels, Sebastian Y. F., et al.
Publicado: (2017)

Burkitt’s lymphoma of the prostate presenting as acute urinary retention: a case report
por: Derigs, Marcus, et al.
Publicado: (2020)

Aberrant Expression of Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) in Warthin Tumors
por: Mandic, Robert, et al.
Publicado: (2020)

MODL-02. TARGETING REPLICATION STRESS IN PEDIATRIC BRAIN TUMORS
por: Krausert, Sonja, et al.
Publicado: (2020)

Challenging ChatGPT 3.5 in Senology—An Assessment of Concordance with Breast Cancer Tumor Board Decision Making
por: Griewing, Sebastian, et al.
Publicado: (2023)

Circulating Tumor Biomarkers in Meningiomas Reveal a Signature of Equilibrium Between Tumor Growth and Immune Modulation
por: Erkan, Erdogan Pekcan, et al.
Publicado: (2019)

The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans
por: Mack, Hildegard I. D., et al.
Publicado: (2017)

High expression of insulinoma‐associated protein 1 (INSM1) distinguishes colorectal mixed and pure neuroendocrine carcinomas from conventional adenocarcinomas with diffuse expression of synaptophysin
por: Litmeyer, Anne‐Sophie, et al.
Publicado: (2023)

CUX1—Transcriptional Master Regulator of Tumor Progression in Pancreatic Neuroendocrine Tumors
por: Krug, Sebastian, et al.
Publicado: (2020)

Hypofractionated radiotherapy has the potential for second cancer reduction
por: Schneider, Uwe, et al.
Publicado: (2010)

The Acetyltransferase RibT From Bacillus subtilis Affects in vivo Dynamics of the Multimeric Heavy Riboflavin Synthase Complex
por: Rotter, Daniel Andreas Orlando, et al.
Publicado: (2022)

The ghost of pandemics past
por: Mack, Thomas M
Publicado: (2005)

Superior Overall Survival in Patients with Colorectal Cancer, Regular Aspirin Use, and Combined Wild-Type PIK3CA and KRAS-Mutated Tumors
por: Gebauer, Leonie, et al.
Publicado: (2021)

Low dose DTIC is effective and safe in pretreated patients with well differentiated neuroendocrine tumors
por: Mueller, Daniela, et al.
Publicado: (2016)

Vessel-Sparing Lymphadenectomy Should Be Performed in Small Intestine Neuroendocrine Neoplasms
por: Bartsch, Detlef K., et al.
Publicado: (2022)

Let us talk about death: gender effects in cancer patients’ preferences for end-of-life discussions
por: Seifart, C., et al.
Publicado: (2020)

Late relapsing germ cell tumors with elevated tumor markers
por: Che, Yue, et al.
Publicado: (2021)

Multinodular and Vacuolating Neuronal Tumor: Incidental Diagnosis of a Rare Brain Lesion
por: Arbuiso, Sophia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jcoenc3eeqfp1kbioleh7kcuks