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Regulatory T-Cells Suppress Cytotoxic T Lymphocyte Responses against Microglia

Regulatory T-cells (Tregs) play pivotal roles during infection, cancer, and autoimmunity. In our previous study, we demonstrated a role for the PD-1:PD-L1 pathway in controlling cytolytic responses of CD8(+) T lymphocytes against microglial cells presenting viral peptides. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Chauhan, Priyanka, Hu, Shuxian, Sheng, Wen S., Lokensgard, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496959/
https://www.ncbi.nlm.nih.gov/pubmed/36139401
http://dx.doi.org/10.3390/cells11182826