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Regulation of cGAS Activity and Downstream Signaling

Cyclic GMP-AMP synthase (cGAS) is a predominant and ubiquitously expressed cytosolic onfirmedDNA sensor that activates innate immune responses by producing a second messenger, cyclic GMP-AMP (cGAMP), and the stimulator of interferon genes (STING). cGAS contains a highly disordered N-terminus, which...

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Detalles Bibliográficos
Autores principales:	Joshi, Bhagwati, Joshi, Jagdish Chandra, Mehta, Dolly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496985/ https://www.ncbi.nlm.nih.gov/pubmed/36139387 http://dx.doi.org/10.3390/cells11182812

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