Cargando…

Expression of Nectin-4 in Variant Histologies of Bladder Cancer and Its Prognostic Value—Need for Biomarker Testing in High-Risk Patients?

SIMPLE SUMMARY: Variant histologies of bladder cancer present at advanced stage and are often treated with radical cystectomy. As Nectin-4 appears to be a promising target for novel therapies in conventional bladder cancer, we aimed to analyze the expression of Nectin-4 and its prognostic value in v...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rodler, Severin, Eismann, Lennert, Schlenker, Boris, Casuscelli, Jozefina, Brinkmann, Isabel, Sendelhofert, Andrea, Waidelich, Raphaela, Buchner, Alexander, Stief, Christian, Schulz, Gerald Bastian, Ledderose, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497069/ https://www.ncbi.nlm.nih.gov/pubmed/36139571 http://dx.doi.org/10.3390/cancers14184411

Ejemplares similares

Identification of the Tumor Infiltrating Lymphocytes (TILs) Landscape in Pure Squamous Cell Carcinoma of the Bladder
por: Eismann, Lennert, et al.
Publicado: (2022)

Accuracy and prognostic value of radiological lymph node features in variant histologies of bladder cancer
por: Rodler, Severin, et al.
Publicado: (2022)

Outcomes and Prognostic Factors of Patients with Urothelial Carcinoma Undergoing Radical Cystectomy and pT0 in the Final Histology Without Neoadjuvant Chemotherapy
por: Rodler, Severin, et al.
Publicado: (2022)

P2X1 and P2X7 Receptor Overexpression Is a Negative Predictor of Survival in Muscle-Invasive Bladder Cancer
por: Ledderose, Stephan, et al.
Publicado: (2023)

Telehealth in Uro-oncology Beyond the Pandemic: Toll or Lifesaver?
por: Rodler, Severin, et al.
Publicado: (2020)

Lessons from the coronavirus disease 2019 pandemic: Will virtual patient management reshape uro-oncology in Germany?
por: Rodler, Severin, et al.
Publicado: (2020)

Computed-tomography based scoring system predicts outcome for clinical lymph node-positive patients undergoing radical cystectomy
por: Eismann, Lennert, et al.
Publicado: (2021)

Confronting hidden COVID-19 burden: a telemedical solution for elective urological outpatient clinics
por: Westhofen, Thilo, et al.
Publicado: (2020)

Prognostic impact of perioperative blood transfusions on oncological outcomes of patients with bladder cancer undergoing radical cystectomy: A systematic review
por: Volz, Yannic, et al.
Publicado: (2020)

Strategies to successfully prevent COVID-19 outbreak in vulnerable uro-oncology patient population
por: Tamalunas, Alexander, et al.
Publicado: (2022)

Image-Guided Robotic Radiosurgery for the Treatment of Lung Metastases of Renal Cell Carcinoma—A Retrospective, Single Center Analysis
por: Rodler, Severin, et al.
Publicado: (2022)

Sequential Treatment Based on Sunitinib and Sorafenib in Patients with Metastatic Renal Cell Carcinoma
por: Schlemmer, Marcus, et al.
Publicado: (2019)

Absence of detrusor muscle in TUR-BT specimen – can we predict who is at highest risk?
por: Volz, Yannic, et al.
Publicado: (2023)

Gender Bias in Urology: How Do Patients Really Choose Their Urologist?
por: Tamalunas, Alexander, et al.
Publicado: (2022)

Heterogenous NECTIN4 expression in urothelial high-risk non-muscle-invasive bladder cancer
por: Garczyk, Stefan, et al.
Publicado: (2022)

Safety and Efficacy of Robotic Radiosurgery for Visceral and Lymph Node Metastases of Renal Cell Carcinoma: A Retrospective, Single Center Analysis
por: Rodler, Severin, et al.
Publicado: (2021)

Polyethylene glycol-coated collagen patch (hemopatch(®)) in open partial nephrectomy
por: Staehler, Michael, et al.
Publicado: (2021)

Partial Nephrectomy in pT3a Tumors Less Than 7 cm in Diameter Has a Superior Overall Survival Compared to Radical Nephrectomy
por: Ziegelmueller, Brigitte K, et al.
Publicado: (2019)

Prospective comparison of one year follow-up outcomes for the open complete intrafascial retropubic versus interfascial nerve-sparing radical prostatectomy
por: Khoder, Wael Y, et al.
Publicado: (2014)

Feasibility of [(68)Ga]Ga-FAPI-46 PET/CT for detection of nodal and hematogenous spread in high-grade urothelial carcinoma
por: Unterrainer, Lena M., et al.
Publicado: (2022)

Local epidemiology and resistance profiles in acute uncomplicated cystitis (AUC) in women: a prospective cohort study in an urban urological ambulatory setting
por: Seitz, Michael, et al.
Publicado: (2017)

Diagnostic and Prognostic Roles of Urine Nectin-2 and Nectin-4 in Human Bladder Cancer
por: Miyake, Makito, et al.
Publicado: (2023)

Epidemiology and Treatment Barriers of Patients With Erectile Dysfunction Using an Online Prescription Platform: A Cross-Sectional Study
por: Rodler, Severin, et al.
Publicado: (2020)

Total Penectomy for Recurrent Chordoma of the Corpus Cavernosum
por: Eismann, Lennert, et al.
Publicado: (2020)

Efficacy and safety of Ho:YAG Laser Lithotripsy for ureteroscopic removal of proximal and distal ureteral calculi
por: Khoder, Wael Y, et al.
Publicado: (2014)

Tracing the evolution of nectin and nectin-like cell adhesion molecules
por: Duraivelan, Kheerthana, et al.
Publicado: (2020)

Inhibition of neurogenic contractions in renal arteries and of cholinergic contractions in coronary arteries by the presumed inhibitor of ADP-ribosylation factor 6, NAV2729
por: Huang, Ru, et al.
Publicado: (2022)

Expression of nectin-4 in papillary renal cell carcinoma
por: Zschäbitz, Stefanie, et al.
Publicado: (2022)

Fournier´s Gangrene Under Sodium-Glucose Cotransporter 2 Inhibitor Therapy as a Life-Threatening Adverse Event: A Case Report and Review of the Literature
por: Rodler, Severin, et al.
Publicado: (2019)

Nectin-4 is a new histological and serological tumor associated marker for breast cancer
por: Fabre-Lafay, Stéphanie, et al.
Publicado: (2007)

Nectin expression in pancreatic adenocarcinoma: nectin-3 is associated with a poor prognosis
por: Izumi, Hideki, et al.
Publicado: (2015)

Laparoscopic repair of iatrogenic bladder perforation during transurethral bladder tumor resection: Case report and literature review
por: May, Florian, et al.
Publicado: (2013)

p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis
por: Mollo, Maria Rosaria, et al.
Publicado: (2015)

Con-nectin axons and dendrites
por: Beaudoin, Gerard M.J.
Publicado: (2006)

Adverse Pathology after Radical Prostatectomy of Patients Eligible for Active Surveillance—A Summary 7 Years after Introducing mpMRI-Guided Biopsy in a Real-World Setting
por: Ebner, Benedikt, et al.
Publicado: (2023)

Radiomics for the Prediction of Overall Survival in Patients with Bladder Cancer Prior to Radical Cystectomy
por: Woźnicki, Piotr, et al.
Publicado: (2022)

Honokiol, a constituent of Magnolia species, inhibits adrenergic contraction of human prostate strips and induces stromal cell death
por: Herrmann, Daniel, et al.
Publicado: (2014)

Concentration-dependent alpha(1)-Adrenoceptor Antagonism and Inhibition of Neurogenic Smooth Muscle Contraction by Mirabegron in the Human Prostate
por: Huang, Ru, et al.
Publicado: (2021)

Inhibition of α(1)-Adrenergic, Non-Adrenergic and Neurogenic Human Prostate Smooth Muscle Contraction and of Stromal Cell Growth by the Isoflavones Genistein and Daidzein
por: Huang, Ru, et al.
Publicado: (2022)

Combined Open Prostatectomy and Kidney Surgery: Feasibility and 12-Month Outcome
por: Rath, Lukas, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_37d77c3nsj4i6mu81aiuqdoejk