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Preclinical Evaluation of Novel Tyrosine-Kinase Inhibitors in Medullary Thyroid Cancer

SIMPLE SUMMARY: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor arising from parafollicular calcitonin-secreting C cells of the thyroid. Most of the patients affected by MTC, especially the familial form, harbor a mutation of the RET proto-oncogene. In patients with advanced disease, med...

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Detalles Bibliográficos
Autores principales: Saronni, Davide, Gaudenzi, Germano, Dicitore, Alessandra, Carra, Silvia, Cantone, Maria Celeste, Borghi, Maria Orietta, Barbieri, Andrea, Mignani, Luca, Hofland, Leo J., Persani, Luca, Vitale, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497079/
https://www.ncbi.nlm.nih.gov/pubmed/36139603
http://dx.doi.org/10.3390/cancers14184442