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Farnesoid X Receptor Overexpression Decreases the Migration, Invasion and Angiogenesis of Human Bladder Cancers via AMPK Activation and Cholesterol Biosynthesis Inhibition

SIMPLE SUMMARY: Our previous studies characterized that FXR overexpression results in the inhibition of migratory, adhesive and angiogenic abilities through the proteosome degradation pathway in human bladder cancer cells. Since cholesterol metabolism plays an important role during cancer progressio...

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Detalles Bibliográficos
Autores principales: Lai, Chien-Rui, Tsai, Yu-Ling, Tsai, Wen-Chiuan, Chen, Tzu-Min, Chang, Hsin-Han, Changchien, Chih-Ying, Wu, Sheng-Tang, Wang, Hisao-Hsien, Chen, Ying, Lin, Yu-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497084/
https://www.ncbi.nlm.nih.gov/pubmed/36139556
http://dx.doi.org/10.3390/cancers14184398