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Farnesoid X Receptor Overexpression Decreases the Migration, Invasion and Angiogenesis of Human Bladder Cancers via AMPK Activation and Cholesterol Biosynthesis Inhibition
SIMPLE SUMMARY: Our previous studies characterized that FXR overexpression results in the inhibition of migratory, adhesive and angiogenic abilities through the proteosome degradation pathway in human bladder cancer cells. Since cholesterol metabolism plays an important role during cancer progressio...
Autores principales: | Lai, Chien-Rui, Tsai, Yu-Ling, Tsai, Wen-Chiuan, Chen, Tzu-Min, Chang, Hsin-Han, Changchien, Chih-Ying, Wu, Sheng-Tang, Wang, Hisao-Hsien, Chen, Ying, Lin, Yu-Huei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497084/ https://www.ncbi.nlm.nih.gov/pubmed/36139556 http://dx.doi.org/10.3390/cancers14184398 |
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