The BET Protein Inhibitor JQ1 Decreases Hypoxia and Improves the Therapeutic Benefit of Anti-PD-1 in a High-Risk Neuroblastoma Mouse Model

Anti-programmed death 1 (PD-1) is a revolutionary treatment for many cancers. The response to anti-PD-1 relies on several properties of tumor and immune cells, including the expression of PD-L1 and PD-1. Despite the impressive clinical benefit achieved with anti-PD-1 in several cancers in adults, th...

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Detalles Bibliográficos
Autores principales: Sauvage, Delphine, Bosseler, Manon, Viry, Elodie, Kanli, Georgia, Oudin, Anais, Berchem, Guy, Keunen, Olivier, Janji, Bassam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497090/
https://www.ncbi.nlm.nih.gov/pubmed/36139358
http://dx.doi.org/10.3390/cells11182783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497090/
https://www.ncbi.nlm.nih.gov/pubmed/36139358
http://dx.doi.org/10.3390/cells11182783

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