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RNA-seq and ChIP-seq Identification of Unique and Overlapping Targets of GLI Transcription Factors in Melanoma Cell Lines

SIMPLE SUMMARY: The majority of melanomas show hyperactivation of the MAPK signaling pathway, most often through mutations in BRAF and NRAS. Despite significant progress in therapy, targeting this signaling pathway solely has not been the solution for stopping the progression of this disease. Recent...

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Detalles Bibliográficos
Autores principales: Kurtović, Matea, Piteša, Nikolina, Bartoniček, Nenad, Ozretić, Petar, Musani, Vesna, Čonkaš, Josipa, Petrić, Tina, King, Cecile, Sabol, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497141/
https://www.ncbi.nlm.nih.gov/pubmed/36139698
http://dx.doi.org/10.3390/cancers14184540