Cargando…

Ceramide Kinase (CERK) Emerges as a Common Therapeutic Target for Triple Positive and Triple Negative Breast Cancer Cells

SIMPLE SUMMARY: Existing chemotherapy treatments for breast cancer patients are high on toxicity. There are very limited options available for triple-positive breast cancer (TPBC) patients, and there have not been any major breakthrough for targeted therapy for triple-negative breast cancer (TNBC) p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rajput, Kajal, Ansari, Mohammad Nafees, Jha, Somesh K., Pani, Trishna, Medatwal, Nihal, Chattopadhyay, Somdeb, Bajaj, Avinash, Dasgupta, Ujjaini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9497187/ https://www.ncbi.nlm.nih.gov/pubmed/36139656 http://dx.doi.org/10.3390/cancers14184496

Ejemplares similares

Alternative splicing of ceramide synthase 2 alters levels of specific ceramides and modulates cancer cell proliferation and migration in Luminal B breast cancer subtype
por: Pani, Trishna, et al.
Publicado: (2021)

Alternative splicing of CERS2 promotes cell proliferation and migration in luminal B subtype breast cancer cells
por: Pani, Trishna, et al.
Publicado: (2021)

A localized hydrogel-mediated chemotherapy causes immunogenic cell death via activation of ceramide-mediated unfolded protein response
por: Kar, Animesh, et al.
Publicado: (2023)

Sorbitol Reduces Sensitivity to Alternaria by Promoting Ceramide Kinases (CERK) Expression through Transcription Factor Pswrky25 in Populus (Populus simonii Carr.)
por: Qi, Meng, et al.
Publicado: (2022)

A Localized Chimeric Hydrogel Therapy Combats Tumor Progression through Alteration of Sphingolipid Metabolism
por: Pal, Sanjay, et al.
Publicado: (2019)

LIK1, A CERK1-Interacting Kinase, Regulates Plant Immune Responses in Arabidopsis
por: Le, Mi Ha, et al.
Publicado: (2014)

The Arabidopsis CERK1‐associated kinase PBL27 connects chitin perception to MAPK activation
por: Yamada, Kenta, et al.
Publicado: (2016)

Presence of LYM2 dependent but CERK1 independent disease resistance in Arabidopsis
por: Narusaka, Yoshihiro, et al.
Publicado: (2013)

Clinical relevance of CERK and SPHK1 in breast cancer and their association with metastasis and drug resistance
por: Bhadwal, Priyanka, et al.
Publicado: (2022)

Arabidopsis ubiquitin ligase PUB12 interacts with and negatively regulates Chitin Elicitor Receptor Kinase 1 (CERK1)
por: Yamaguchi, Koji, et al.
Publicado: (2017)

A phase i study of daily treatment with a ceramide-dominant triple lipid mixture commencing in neonates
por: Lowe, Adrian J, et al.
Publicado: (2012)

The kinase LYK5 is a major chitin receptor in Arabidopsis and forms a chitin-induced complex with related kinase CERK1
por: Cao, Yangrong, et al.
Publicado: (2014)

Triple negative breast cancer: an Indian perspective
por: Akhtar, Murtaza, et al.
Publicado: (2015)

Triple Threat: Triple Pathogen Endocarditis
por: Gonzalez, Jessica M, et al.
Publicado: (2023)

Profiling mitochondrial DNA mutations in tumors and circulating extracellular vesicles of triple‐negative breast cancer patients for potential biomarker development
por: Vikramdeo, Kunwar Somesh, et al.
Publicado: (2023)

Splicing of Receptor-Like Kinase-Encoding SNC4 and CERK1 is Regulated by Two Conserved Splicing Factors that Are Required for Plant Immunity
por: Zhang, Zhibin, et al.
Publicado: (2014)

Extraction Optimization, UHPLC-Triple-TOF-MS/MS Analysis and Antioxidant Activity of Ceramides from Sea Red Rice Bran
por: Wang, Gang, et al.
Publicado: (2022)

Triple
por: Follet, Ken
Publicado: (1990)

Ceramide Synthase 6 Mediates Triple-Negative Breast Cancer Response to Chemotherapy Through RhoA- and EGFR-Mediated Signaling Pathways
por: Chen, Hui, et al.
Publicado: (2022)

“It Takes Two to Tango”: Role of Neglected Macrophage Manipulators Coronin 1 and Protein Kinase G in Mycobacterial Pathogenesis
por: Saha, Saradindu, et al.
Publicado: (2020)

Ceramide kinase mediates intrinsic resistance and inferior response to chemotherapy in triple‐negative breast cancer by upregulating Ras/ERK and PI3K/Akt pathways
por: Zhu, Shan, et al.
Publicado: (2021)

Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate chitin elicitor signaling in rice
por: Shimizu, Takeo, et al.
Publicado: (2010)

The Pattern Recognition Receptor FLS2 Can Shape the Arabidopsis Rhizosphere Microbiome β-Diversity but Not EFR1 and CERK1
por: Fonseca, Jose P., et al.
Publicado: (2022)

Receptor-Like Kinase LYK9 in Pisum sativum L. Is the CERK1-Like Receptor that Controls Both Plant Immunity and AM Symbiosis Development
por: Leppyanen, Irina V., et al.
Publicado: (2017)

Periumbilical laparoscopic surgery through triple channels using common instrumentation
por: GE, JIA-YUN, et al.
Publicado: (2013)

Targeting a cell state common to triple-negative breast cancers
por: Muellner, Markus K, et al.
Publicado: (2015)

Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis
por: Sha, Wei, et al.
Publicado: (2018)

Triple función /
por: Blanco, José Joaquín, 1951-
Publicado: (2007)

Partida triple.

Triple concerto
por: Beethoven, Ludwig van, 1770-1827
Publicado: (1993)

The triple Thinkers
por: Wilson, Edmund, 1895-1972

Triple Qualification
Publicado: (1946)

Triple Amputation
por: Bancroft, F. J.
Publicado: (1874)

Triple trouble
por: Kaplan, Steven Jon
Publicado: (2020)

Triple horror: A rare case of triple metachronous malignancy
por: Biswas, Rituparna, et al.
Publicado: (2019)

Striking the Right Balance Determines TB or Not TB
por: BoseDasgupta, Somdeb, et al.
Publicado: (2014)

Inflammatory Stimuli Reprogram Macrophage Phagocytosis to Macropinocytosis for the Rapid Elimination of Pathogens
por: BoseDasgupta, Somdeb, et al.
Publicado: (2014)

Triple Atresia, Triple Threat? An Unusual Constellation of Primary Surgical Abnormalities
por: Jackson, Raef, et al.
Publicado: (2021)

Triple Threat: Triple-Valve Endocarditis Case Report and Literature Review
por: Vattikonda, Kiriti S., et al.
Publicado: (2023)

Poaceae-specific cell wall-derived oligosaccharides activate plant immunity via OsCERK1 during Magnaporthe oryzae infection in rice
por: Yang, Chao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_vl1sp4kl2kf21acn7h81kraaos